AVT1G_ARATH
ID AVT1G_ARATH Reviewed; 524 AA.
AC Q1PER9; A0MEV0; Q9SR30;
DT 07-JUN-2017, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Amino acid transporter AVT1G {ECO:0000305};
DE Short=AtAvt1G {ECO:0000303|PubMed:27925655};
GN Name=AVT1G {ECO:0000303|PubMed:27925655};
GN OrderedLocusNames=At3g09330 {ECO:0000312|Araport:AT3G09330};
GN ORFNames=F3L24.20 {ECO:0000312|EMBL:AAF14030.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=27925655; DOI=10.1002/1873-3468.12507;
RA Fujiki Y., Teshima H., Kashiwao S., Kawano-Kawada M., Ohsumi Y.,
RA Kakinuma Y., Sekito T.;
RT "Functional identification of AtAVT3, a family of vacuolar amino acid
RT transporters, in Arabidopsis.";
RL FEBS Lett. 591:5-15(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC Amino acid/auxin permease (AAAP) (TC 2.A.18.5) subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF14030.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=ABK28550.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC011436; AAF14030.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE74751.1; -; Genomic_DNA.
DR EMBL; DQ446648; ABE65929.1; -; mRNA.
DR EMBL; DQ653073; ABK28550.1; ALT_SEQ; mRNA.
DR RefSeq; NP_187544.2; NM_111767.3.
DR AlphaFoldDB; Q1PER9; -.
DR SMR; Q1PER9; -.
DR STRING; 3702.AT3G09330.1; -.
DR PaxDb; Q1PER9; -.
DR PRIDE; Q1PER9; -.
DR ProteomicsDB; 241017; -.
DR EnsemblPlants; AT3G09330.1; AT3G09330.1; AT3G09330.
DR GeneID; 820089; -.
DR Gramene; AT3G09330.1; AT3G09330.1; AT3G09330.
DR KEGG; ath:AT3G09330; -.
DR Araport; AT3G09330; -.
DR TAIR; locus:2083529; AT3G09330.
DR eggNOG; KOG1303; Eukaryota.
DR HOGENOM; CLU_009646_1_0_1; -.
DR InParanoid; Q1PER9; -.
DR OMA; VFFYIVV; -.
DR OrthoDB; 570025at2759; -.
DR PhylomeDB; Q1PER9; -.
DR PRO; PR:Q1PER9; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q1PER9; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0003333; P:amino acid transmembrane transport; IBA:GO_Central.
DR InterPro; IPR013057; AA_transpt_TM.
DR Pfam; PF01490; Aa_trans; 1.
PE 2: Evidence at transcript level;
KW Amino-acid transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..524
FT /note="Amino acid transporter AVT1G"
FT /id="PRO_0000440108"
FT TRANSMEM 139..159
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 164..184
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 247..267
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 280..300
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 319..339
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 349..369
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 398..418
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 442..462
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 465..485
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 496..516
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..33
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 524 AA; 57068 MW; 1B75F5F71DD17F7A CRC64;
MELEEQERDI LFPTDDEECQ VDVSCDDEDD DSSSYSSLSQ NDSAPWPRSY RQSVDILTGV
TPPTISFIHR RSSQTSFTSS VASLYKRRPT SIANSFASST SKQPLLSEKD DVLFLSSQIG
LSNTDLSYGE PNFCSFPQSV LNGINVLCGI SLLTMPYAVK EGGWLGLCIL LSFAIITCYT
GILLKRCLES SSDLRTYPDI GQAAFGFTGR LIISILLYME LYVCCVEYII MMSDNLSRVF
PNITLNIVGV SLDSPQIFAI SATLIVLPTV WLKDLSLLSY LSAGGVFVSI LLALCLFWVG
SVDGVGFHTG GKSLDLANLP VAIGIFGFGF SGHAVLPSIY SSMKEPSKFP LVLLISFGFC
VFFYIVVAIC GYSMFGEAIQ SQFTLNMPQQ YTASKIAVWT AVVVPMTKYA LALTPIVLGL
EELMLPSEKM RSYGVSIFIK TILVLSTLVV ALTFPFFAIM GALMGSFLAM LVDFIFPCLC
YLSILKGRLS KTQIGICVFI IISGIVSGCC GTYSAIGRLV GKLD
