AVT1J_ARATH
ID AVT1J_ARATH Reviewed; 423 AA.
AC Q9LXF8;
DT 07-JUN-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Amino acid transporter AVT1J {ECO:0000305};
DE Short=AtAvt1J {ECO:0000303|PubMed:27925655};
GN Name=AVT1J {ECO:0000303|PubMed:27925655};
GN OrderedLocusNames=At5g15240 {ECO:0000312|Araport:AT5G15240};
GN ORFNames=F8M21.130 {ECO:0000312|EMBL:CAB89334.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=27925655; DOI=10.1002/1873-3468.12507;
RA Fujiki Y., Teshima H., Kashiwao S., Kawano-Kawada M., Ohsumi Y.,
RA Kakinuma Y., Sekito T.;
RT "Functional identification of AtAVT3, a family of vacuolar amino acid
RT transporters, in Arabidopsis.";
RL FEBS Lett. 591:5-15(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=Additional isoforms seem to exist. {ECO:0000305};
CC Name=1;
CC IsoId=Q9LXF8-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC Amino acid/auxin permease (AAAP) (TC 2.A.18.5) subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BX829753; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL353993; CAB89334.1; -; Genomic_DNA.
DR EMBL; CP002688; AED92134.1; -; Genomic_DNA.
DR EMBL; BX829753; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; T49959; T49959.
DR RefSeq; NP_197028.1; NM_121528.3. [Q9LXF8-1]
DR AlphaFoldDB; Q9LXF8; -.
DR SMR; Q9LXF8; -.
DR IntAct; Q9LXF8; 13.
DR STRING; 3702.AT5G15240.1; -.
DR PaxDb; Q9LXF8; -.
DR PRIDE; Q9LXF8; -.
DR EnsemblPlants; AT5G15240.1; AT5G15240.1; AT5G15240. [Q9LXF8-1]
DR GeneID; 831376; -.
DR Gramene; AT5G15240.1; AT5G15240.1; AT5G15240. [Q9LXF8-1]
DR KEGG; ath:AT5G15240; -.
DR Araport; AT5G15240; -.
DR TAIR; locus:2150911; AT5G15240.
DR eggNOG; KOG1303; Eukaryota.
DR InParanoid; Q9LXF8; -.
DR OMA; WTHFFAC; -.
DR OrthoDB; 570025at2759; -.
DR PhylomeDB; Q9LXF8; -.
DR PRO; PR:Q9LXF8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LXF8; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0003333; P:amino acid transmembrane transport; IBA:GO_Central.
DR InterPro; IPR013057; AA_transpt_TM.
DR Pfam; PF01490; Aa_trans; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Amino-acid transport; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..423
FT /note="Amino acid transporter AVT1J"
FT /id="PRO_0000440111"
FT TRANSMEM 39..59
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 63..83
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 110..130
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 186..206
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 219..239
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..272
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 297..317
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 333..355
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 359..381
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 390..410
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
SQ SEQUENCE 423 AA; 46473 MW; 2A3432B37F7CA65F CRC64;
MSEDKDYMSE PFIVKKIDDE ESLLDDYNPQ GNTSFSKTCF HGINALSGVG ILSVPYALAS
GGWLSLIILF TVAITTFYCA ILIKRCMEMD PLLRSYPDIG YKAFGNTGRV IVSIFMNLEL
YLVATSFLIL EGDNLNKLFS NVGLNFMGLE FQGKQMFIIM VALIILPSVW LDNMRILSYV
SASGVFASGV ILASIFSVGA FEGVGFKNND SEVFRLNGVA TSVSLYAFCY CAHPVFPTLY
TSMKNKRQFS NVMIICFTIC TFIYASVAVL GYLMYGSDVE SQITLNLPTD KLSSKVAIWT
TLVNPIAKFA LMVTPIIDAM RSRFSRVLPN KRASGFLLST ILVTSNVIVA LLLPFFGDLM
SLVGAFLSAS ASVILPCLCY LKISGKYQRL GFETLVLIGI TLTGIVVVIT GTYQAVKDIF
GRF
