ID   RRF_STRP6               Reviewed;         185 AA.
AC   Q5XDH3; P82556;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Ribosome-recycling factor {ECO:0000255|HAMAP-Rule:MF_00040};
DE            Short=RRF {ECO:0000255|HAMAP-Rule:MF_00040};
DE   AltName: Full=Ribosome-releasing factor {ECO:0000255|HAMAP-Rule:MF_00040};
GN   Name=frr {ECO:0000255|HAMAP-Rule:MF_00040}; OrderedLocusNames=M6_Spy0405;
OS   Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=286636;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-946 / MGAS10394;
RX   PubMed=15272401; DOI=10.1086/422697;
RA   Banks D.J., Porcella S.F., Barbian K.D., Beres S.B., Philips L.E.,
RA   Voyich J.M., DeLeo F.R., Martin J.M., Somerville G.A., Musser J.M.;
RT   "Progress toward characterization of the group A Streptococcus metagenome:
RT   complete genome sequence of a macrolide-resistant serotype M6 strain.";
RL   J. Infect. Dis. 190:727-738(2004).
RN   [2]
RP   PROTEIN SEQUENCE OF 40-72; 81-111; 145-154 AND 163-185, AND MASS
RP   SPECTROMETRY.
RC   STRAIN=JRS4 / Serotype M6;
RA   Hogan D.A., Du P., Stevenson T.I., Whitton M., Kilby G.W., Rogers J.,
RA   VanBogelen R.A.;
RT   "Two-dimensional gel electrophoresis map of Streptococcus pyogenes
RT   proteins.";
RL   Submitted (MAY-2000) to UniProtKB.
CC   -!- FUNCTION: Responsible for the release of ribosomes from messenger RNA
CC       at the termination of protein biosynthesis. May increase the efficiency
CC       of translation by recycling ribosomes from one round of translation to
CC       another. {ECO:0000255|HAMAP-Rule:MF_00040}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00040}.
CC   -!- MASS SPECTROMETRY: Mass=20572.45; Method=Electrospray;
CC       Evidence={ECO:0000269|Ref.2};
CC   -!- SIMILARITY: Belongs to the RRF family. {ECO:0000255|HAMAP-
CC       Rule:MF_00040}.
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DR   EMBL; CP000003; AAT86540.1; -; Genomic_DNA.
DR   RefSeq; WP_002985763.1; NC_006086.1.
DR   AlphaFoldDB; Q5XDH3; -.
DR   SMR; Q5XDH3; -.
DR   EnsemblBacteria; AAT86540; AAT86540; M6_Spy0405.
DR   GeneID; 57852199; -.
DR   KEGG; spa:M6_Spy0405; -.
DR   HOGENOM; CLU_073981_2_0_9; -.
DR   OMA; FNPMNNG; -.
DR   Proteomes; UP000001167; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006415; P:translational termination; IEA:UniProtKB-UniRule.
DR   CDD; cd00520; RRF; 1.
DR   Gene3D; 1.10.132.20; -; 1.
DR   HAMAP; MF_00040; RRF; 1.
DR   InterPro; IPR002661; Ribosome_recyc_fac.
DR   InterPro; IPR023584; Ribosome_recyc_fac_dom.
DR   InterPro; IPR036191; RRF_sf.
DR   PANTHER; PTHR20982; PTHR20982; 1.
DR   Pfam; PF01765; RRF; 1.
DR   SUPFAM; SSF55194; SSF55194; 1.
DR   TIGRFAMs; TIGR00496; frr; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Direct protein sequencing; Protein biosynthesis.
FT   CHAIN           1..185
FT                   /note="Ribosome-recycling factor"
FT                   /id="PRO_0000167556"
SQ   SEQUENCE   185 AA;  20572 MW;  58F63D5300392B6B CRC64;
     MANAIIETAK ERFAQSHQSL SREYASIRAG RANASLLDRI QVDYYGAPTP LNQLASITVP
     EARVLLISPF DKSSIKDIER ALNASDLGIT PANDGSVIRL VIPALTEETR KELAKEVKKV
     GENAKIAIRN IRRDAMDDAK KQEKAKEITE DELKTLEKDI QKATDDAIKE IDRMTAEKEK
     ELLSV