AVT6B_ARATH
ID AVT6B_ARATH Reviewed; 456 AA.
AC F4KBM7; Q9FMC0;
DT 07-JUN-2017, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Amino acid transporter AVT6B {ECO:0000305};
DE Short=AtAvt6B {ECO:0000303|PubMed:27925655};
GN Name=AVT6B {ECO:0000303|PubMed:27925655};
GN OrderedLocusNames=At5g38820 {ECO:0000312|Araport:AT5G38820};
GN ORFNames=K15E6.7 {ECO:0000312|EMBL:BAB08638.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=27925655; DOI=10.1002/1873-3468.12507;
RA Fujiki Y., Teshima H., Kashiwao S., Kawano-Kawada M., Ohsumi Y.,
RA Kakinuma Y., Sekito T.;
RT "Functional identification of AtAVT3, a family of vacuolar amino acid
RT transporters, in Arabidopsis.";
RL FEBS Lett. 591:5-15(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC Amino acid/auxin permease (AAAP) (TC 2.A.18.6) subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ANM68525.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAB08638.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AB009048; BAB08638.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED94363.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM68525.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; ANM68526.1; -; Genomic_DNA.
DR RefSeq; NP_001318700.1; NM_001344269.1.
DR RefSeq; NP_001330273.1; NM_001344270.1.
DR RefSeq; NP_198698.1; NM_123243.1.
DR AlphaFoldDB; F4KBM7; -.
DR SMR; F4KBM7; -.
DR STRING; 3702.AT5G38820.1; -.
DR PaxDb; F4KBM7; -.
DR PRIDE; F4KBM7; -.
DR ProteomicsDB; 241159; -.
DR EnsemblPlants; AT5G38820.1; AT5G38820.1; AT5G38820.
DR EnsemblPlants; AT5G38820.3; AT5G38820.3; AT5G38820.
DR GeneID; 833873; -.
DR Gramene; AT5G38820.1; AT5G38820.1; AT5G38820.
DR Gramene; AT5G38820.3; AT5G38820.3; AT5G38820.
DR KEGG; ath:AT5G38820; -.
DR Araport; AT5G38820; -.
DR TAIR; locus:2166615; AT5G38820.
DR eggNOG; KOG1305; Eukaryota.
DR HOGENOM; CLU_034419_2_0_1; -.
DR InParanoid; F4KBM7; -.
DR OrthoDB; 697331at2759; -.
DR PRO; PR:F4KBM7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4KBM7; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015179; F:L-amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0003333; P:amino acid transmembrane transport; IBA:GO_Central.
DR InterPro; IPR013057; AA_transpt_TM.
DR Pfam; PF01490; Aa_trans; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..456
FT /note="Amino acid transporter AVT6B"
FT /id="PRO_0000440113"
FT TRANSMEM 37..57
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..78
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 118..138
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 164..184
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 191..211
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 236..256
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 273..293
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 328..348
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 365..385
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 388..408
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 423..443
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
SQ SEQUENCE 456 AA; 49678 MW; 551E7B20057D8E13 CRC64;
MENLDEIRTD IVESTAPLLQ ESSSESNGGG EFNGASFSGA VFNLATTIIG AGIMALPATM
KILGLIPGIT IIVLMAFLTD ASIEFLLRFS NIGNQRSYGG VMDDSFGKCG RIMLQVSILV
SNIGVLIVYM IIIGDVLAGK NEYGIHHAGM LEGWFGISWW NRRTFVLLVT TLTVFAPLTC
FKRIDSLRFT SAISVALAVV FLVITAGITI IKLFTDGLMM PRLLPNVTDL SSFWKLFTVV
PVLVNAYICH YNVHSIQNEL EDPSRIKPVV RSALAMCSSV YVMTSLFGYL LFGDGTLDDV
LANFDTDLGI PFGSVLNDAV RFSYAAHLML VFPVVFYPLR INIDGLIFPT APPLTSSESD
LRFGSITAGL IAVIFLGANF IPSIWDAFQF TGATAAVCIG FIFPAAVILK DRHNQATKRD
KTIAICMIVL AVFSNAIAIY SDAYALFKKH TYVYPI
