ID   RRG1_KLULA              Reviewed;         380 AA.
AC   Q6CK85;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Required for respiratory growth protein 1, mitochondrial;
GN   Name=RRG1; OrderedLocusNames=KLLA0F12694g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Essential for respiratory growth and required for
CC       mitochondrial protein synthesis. Required for vacuolar acidification
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRG1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR382126; CAG98362.1; -; Genomic_DNA.
DR   RefSeq; XP_455654.1; XM_455654.1.
DR   AlphaFoldDB; Q6CK85; -.
DR   SMR; Q6CK85; -.
DR   STRING; 28985.XP_455654.1; -.
DR   EnsemblFungi; CAG98362; CAG98362; KLLA0_F12694g.
DR   GeneID; 2895806; -.
DR   KEGG; kla:KLLA0_F12694g; -.
DR   eggNOG; ENOG502RYGE; Eukaryota.
DR   HOGENOM; CLU_062256_0_0_1; -.
DR   InParanoid; Q6CK85; -.
DR   OMA; WYRYTLR; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..380
FT                   /note="Required for respiratory growth protein 1,
FT                   mitochondrial"
FT                   /id="PRO_0000402246"
SQ   SEQUENCE   380 AA;  45095 MW;  1D7863E3474C23F1 CRC64;
     MVRPFGEIGS HRKHVLEWYR YSLRNIRANV PTDNLQIELW NTLRQAVRRN RNHKAGWYVR
     GLLEDLSHLN KYIVGDDIIK LVALKNKYTE QIEPAPEPLQ QANKPISGVV VTENMGDESR
     REKKKRLAPI PGDGDLYRYL LRYYKIYGPT KTIPRKHIDE LLRPLAIHER YCKILYRIEY
     RIAKGPPKVS INYTNAGQSR IWFIRSPFNR KARQSKKLTG IIIKARLRAQ DNLDRFRECE
     SKLFYAFQEA QWEYTLIHKQ PCSRKFNDVV TQIKSGKSND IPAVFIDWIK PILEDMDILN
     RINANTQRKF TESRDHLIDG KQYEYYKQLN QRLYKKRLER FLGLKAELPT TNPFTEEKNL
     GALLVKWRFL RPDQLVKVKS