AVT6D_ARATH
ID AVT6D_ARATH Reviewed; 440 AA.
AC Q0WQJ3; Q8S8E1;
DT 07-JUN-2017, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Amino acid transporter AVT6D {ECO:0000305};
DE Short=AtAvt6D {ECO:0000303|PubMed:27925655};
GN Name=AVT6D {ECO:0000303|PubMed:27925655};
GN OrderedLocusNames=At2g40420 {ECO:0000312|Araport:AT2G40420};
GN ORFNames=T3G21.19 {ECO:0000312|EMBL:AAM15348.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=27925655; DOI=10.1002/1873-3468.12507;
RA Fujiki Y., Teshima H., Kashiwao S., Kawano-Kawada M., Ohsumi Y.,
RA Kakinuma Y., Sekito T.;
RT "Functional identification of AtAVT3, a family of vacuolar amino acid
RT transporters, in Arabidopsis.";
RL FEBS Lett. 591:5-15(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC Amino acid/auxin permease (AAAP) (TC 2.A.18.6) subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM15348.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC007020; AAM15348.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC09826.1; -; Genomic_DNA.
DR EMBL; AK228702; BAF00606.1; -; mRNA.
DR PIR; C84829; C84829.
DR RefSeq; NP_181573.3; NM_129602.5.
DR AlphaFoldDB; Q0WQJ3; -.
DR SMR; Q0WQJ3; -.
DR STRING; 3702.AT2G40420.1; -.
DR PaxDb; Q0WQJ3; -.
DR PRIDE; Q0WQJ3; -.
DR ProteomicsDB; 240940; -.
DR EnsemblPlants; AT2G40420.1; AT2G40420.1; AT2G40420.
DR GeneID; 818635; -.
DR Gramene; AT2G40420.1; AT2G40420.1; AT2G40420.
DR KEGG; ath:AT2G40420; -.
DR Araport; AT2G40420; -.
DR TAIR; locus:2063068; AT2G40420.
DR eggNOG; KOG1305; Eukaryota.
DR HOGENOM; CLU_034419_2_0_1; -.
DR InParanoid; Q0WQJ3; -.
DR OMA; FAFTGHQ; -.
DR OrthoDB; 1109791at2759; -.
DR PhylomeDB; Q0WQJ3; -.
DR PRO; PR:Q0WQJ3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q0WQJ3; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0015179; F:L-amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0003333; P:amino acid transmembrane transport; IBA:GO_Central.
DR InterPro; IPR013057; AA_transpt_TM.
DR Pfam; PF01490; Aa_trans; 1.
PE 2: Evidence at transcript level;
KW Amino-acid transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..440
FT /note="Amino acid transporter AVT6D"
FT /id="PRO_0000440115"
FT TRANSMEM 26..46
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 47..67
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 149..169
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 182..202
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 219..239
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 262..282
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 309..329
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 356..376
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 377..397
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 410..430
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
SQ SEQUENCE 440 AA; 47670 MW; ADA715EADF2EBF8A CRC64;
MSPAIKAPLL PNQEPSSSSS ENHGSFAGAV FNISTSIVGA GIMAIPAAFK VLGVIPSLSI
IVIIAWLSNV SAGFLMKSSL AGESTTYAGV MKESFGKSGA VAVTVVTMVV TFGSMIIFSI
IIGDVISGNE KDGIIHLGLL QEWFGSHWWN TRFFGLLFIF VFLFLPLVLC RRVERLAFSS
AISFLLALLF VVISSVLAII ALVQGKTKPP RLFPELNDGG LSFFSLFTAS PVIVTAFTFH
FNVHPVAFEL KDPLNVLSAT RISVILCATI YSATGLFCYL LFGDSTMTDV LMNFDQSTSS
SVGSLLNDIV RLSYAIHLML VFPLLNFSLR ANLDELLFPM KLSLVEDNKR FFALTFPLLI
SCFLGAIAIP DIWYFFQFLG STSTVSIAFI FPAAIVLRNV NGFSTLREKI VASVMLVLAV
ATSIIAISTN IYTFTATEET
