ID   RRG8_KLULA              Reviewed;         282 AA.
AC   Q6CQQ8;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Required for respiratory growth protein 8, mitochondrial;
GN   Name=RRG8; OrderedLocusNames=KLLA0D15125g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for respiratory activity and maintenance and
CC       expression of the mitochondrial genome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRG8 family. {ECO:0000305}.
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DR   EMBL; CR382124; CAH00827.1; -; Genomic_DNA.
DR   RefSeq; XP_453731.1; XM_453731.1.
DR   AlphaFoldDB; Q6CQQ8; -.
DR   STRING; 28985.XP_453731.1; -.
DR   EnsemblFungi; CAH00827; CAH00827; KLLA0_D15125g.
DR   GeneID; 2893395; -.
DR   KEGG; kla:KLLA0_D15125g; -.
DR   eggNOG; ENOG502S46Y; Eukaryota.
DR   HOGENOM; CLU_090059_0_0_1; -.
DR   InParanoid; Q6CQQ8; -.
DR   OMA; FHRWAGK; -.
DR   Proteomes; UP000000598; Chromosome D.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IEA:InterPro.
DR   InterPro; IPR031415; Rrg8.
DR   Pfam; PF17068; RRG8; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..282
FT                   /note="Required for respiratory growth protein 8,
FT                   mitochondrial"
FT                   /id="PRO_0000405466"
SQ   SEQUENCE   282 AA;  31864 MW;  C78AC86C974E706F CRC64;
     MSKGWRKLFV SRGDGTKNSL KKTLKVPEVR SPLLTNFHRW AGKERVLKLT DKEQVTEAVG
     NSSWDLSKNL FANLLASPMR SDKASRFKFP RDLLIQMKLV QTGNENPGKL ATLMPLINMK
     SGKSSSYVAN SLKIFKGKKP GLGQLVPTAV NDSGIANISL SDIVLDKSLF TEKHQEELLQ
     CIENCMTQLV DRRKSSVPVV VEDWDVVLTY DHNNDNDIEL VRLKQLPKDP TVIILNLKVV
     ENDSIRALIN DKLKNHEVGV VLKFLKDERL IRLVYSLLNF SK