ID   RRG8_LACTC              Reviewed;         278 AA.
AC   C5DHM2;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=Required for respiratory growth protein 8, mitochondrial;
GN   Name=RRG8; OrderedLocusNames=KLTH0E05500g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Required for respiratory activity and maintenance and
CC       expression of the mitochondrial genome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRG8 family. {ECO:0000305}.
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DR   EMBL; CU928169; CAR23283.1; -; Genomic_DNA.
DR   RefSeq; XP_002553720.1; XM_002553674.1.
DR   AlphaFoldDB; C5DHM2; -.
DR   STRING; 559295.C5DHM2; -.
DR   PRIDE; C5DHM2; -.
DR   EnsemblFungi; CAR23283; CAR23283; KLTH0E05500g.
DR   GeneID; 8291873; -.
DR   KEGG; lth:KLTH0E05500g; -.
DR   eggNOG; ENOG502S46Y; Eukaryota.
DR   HOGENOM; CLU_090059_0_0_1; -.
DR   InParanoid; C5DHM2; -.
DR   OMA; IRCERMA; -.
DR   OrthoDB; 1452891at2759; -.
DR   Proteomes; UP000002036; Chromosome E.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IEA:InterPro.
DR   InterPro; IPR031415; Rrg8.
DR   Pfam; PF17068; RRG8; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..278
FT                   /note="Required for respiratory growth protein 8,
FT                   mitochondrial"
FT                   /id="PRO_0000405467"
SQ   SEQUENCE   278 AA;  31307 MW;  C739946694F5F1F4 CRC64;
     MSKPSVLKGC LESLVALEKT KRIPKKPSCD ASPLISNFEN WSGKPRKLYL RDARSMKRQG
     LPYELNSNMF AQLLASPMRL DKITRVRAPK ELLVQIKLRK ADTDISAARG KPFELRPSFG
     MERGHPTSYV SNSVALVHKY ASSAMKWLPS SANSTIRHIN QADVATQPEW YSQAYTEQML
     GSLREALSST LMHLGKAPES DPRDVIIVCN PQLPAISLRK SENPFIALAT TVLNLYPIKD
     PELEKVVNNR DIELCSSKHR SLCFLIYRLL AFQADRII