RRG9_COCP7
ID RRG9_COCP7 Reviewed; 264 AA.
AC C5PBQ8;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-SEP-2009, sequence version 1.
DT 25-MAY-2022, entry version 42.
DE RecName: Full=Required for respiratory growth protein 9, mitochondrial;
DE Flags: Precursor;
GN Name=RRG9; ORFNames=CPC735_064850;
OS Coccidioides posadasii (strain C735) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=222929;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C735;
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- FUNCTION: Required for respiratory activity and maintenance and
CC expression of the mitochondrial genome. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRG9 family. {ECO:0000305}.
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DR EMBL; ACFW01000041; EER25385.1; -; Genomic_DNA.
DR RefSeq; XP_003067530.1; XM_003067484.1.
DR AlphaFoldDB; C5PBQ8; -.
DR SMR; C5PBQ8; -.
DR EnsemblFungi; EER25385; EER25385; CPC735_064850.
DR GeneID; 9693013; -.
DR KEGG; cpw:CPC735_064850; -.
DR VEuPathDB; FungiDB:CPC735_064850; -.
DR HOGENOM; CLU_1053773_0_0_1; -.
DR Proteomes; UP000009084; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR InterPro; IPR010487; NGRN/Rrg9.
DR PANTHER; PTHR13475; PTHR13475; 1.
DR Pfam; PF06413; Neugrin; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Transit peptide.
FT TRANSIT 1..12
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 13..264
FT /note="Required for respiratory growth protein 9,
FT mitochondrial"
FT /id="PRO_0000407945"
FT REGION 86..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..237
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 264 AA; 30646 MW; 67B8160C3317AAA6 CRC64;
MFGITSRPYH RWSSFAQALR ILQSGTTLAL ELDHSSLFFS KRNITSCCHH TKPASHTPTS
SNSIWTPSPL AESRLRSGYS LKPAHTNRVV TRRYASTTPK DSQPDPQAKT VSKRPAKKME
QWRLQKEALK KKFQEGWAPP KRLSPDAIEG VRELHQQNPQ KFSTAVLAEH FKMSPEAIRR
ILKSKWRPSE KEMEKRRERW ERRETRIWDH MSELGLRPLR KRPSSPASDK SSDAETRNRQ
PLHSIASTLL IQRDISPMWV LLLR