RRN11_SCHPO
ID RRN11_SCHPO Reviewed; 200 AA.
AC O94332;
DT 06-DEC-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 118.
DE RecName: Full=RNA polymerase I-specific transcription initiation factor rrn11;
GN Name=rrn11; ORFNames=SPBC725.17c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP IDENTIFICATION, AND FUNCTION.
RX PubMed=12095692; DOI=10.1016/s0378-1119(02)00597-8;
RA Boukhgalter B., Liu M., Guo A., Tripp M., Tran K., Huynh C., Pape L.;
RT "Characterization of a fission yeast subunit of an RNA polymerase I
RT essential transcription initiation factor, SpRrn7h/TAF(I)68, that bridges
RT yeast and mammals: association with SpRrn11h and the core ribosomal RNA
RT gene promoter.";
RL Gene 291:187-201(2002).
CC -!- FUNCTION: Subunit of a multiprotein complex essential for the
CC initiation of rDNA transcription by RNA polymerase I. Binding to the
CC DNA template is dependent on the initial binding of other factors.
CC {ECO:0000269|PubMed:12095692}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; CU329671; CAA22189.1; -; Genomic_DNA.
DR PIR; T40669; T40669.
DR RefSeq; NP_595497.1; NM_001021408.2.
DR AlphaFoldDB; O94332; -.
DR SMR; O94332; -.
DR BioGRID; 277698; 11.
DR STRING; 4896.SPBC725.17c.1; -.
DR MaxQB; O94332; -.
DR PaxDb; O94332; -.
DR EnsemblFungi; SPBC725.17c.1; SPBC725.17c.1:pep; SPBC725.17c.
DR GeneID; 2541184; -.
DR KEGG; spo:SPBC725.17c; -.
DR PomBase; SPBC725.17c; rrn11.
DR VEuPathDB; FungiDB:SPBC725.17c; -.
DR eggNOG; ENOG502SC4N; Eukaryota.
DR HOGENOM; CLU_1327064_0_0_1; -.
DR InParanoid; O94332; -.
DR OMA; WNIGLEI; -.
DR PhylomeDB; O94332; -.
DR PRO; PR:O94332; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0032153; C:cell division site; HDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0072686; C:mitotic spindle; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0070860; C:RNA polymerase I core factor complex; ISO:PomBase.
DR GO; GO:0000120; C:RNA polymerase I transcription regulator complex; IDA:PomBase.
DR GO; GO:0001164; F:RNA polymerase I core promoter sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0001181; F:RNA polymerase I general transcription initiation factor activity; IDA:PomBase.
DR GO; GO:0017025; F:TBP-class protein binding; IBA:GO_Central.
DR GO; GO:0042790; P:nucleolar large rRNA transcription by RNA polymerase I; IBA:GO_Central.
DR GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; IDA:PomBase.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR007224; TIF_Rrn11.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF04090; RNA_pol_I_TF; 1.
DR SUPFAM; SSF48452; SSF48452; 1.
PE 4: Predicted;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..200
FT /note="RNA polymerase I-specific transcription initiation
FT factor rrn11"
FT /id="PRO_0000097446"
SQ SEQUENCE 200 AA; 23183 MW; 2FD0D16B0E1CBEB2 CRC64;
MFSPCTVKEK RSTLRSVAPN PESSVIPPIP LPSRRYKTRH IDALCSLMHL CLLRKDYPRA
SRAFSLLLRS KSVDISKLWN IGLEILNKVN PEASSEYMER LIARYPARPS INNSYPNRNA
EHFFPAYIML LIQRQEYNKA MKLLDEYLLL PPYNQNPALH EYSGMLCFEL AKEEASESER
TKWIEKAKYN FSNAGIDVEL