ID   RRN3_SCHPO              Reviewed;         599 AA.
AC   Q10110;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 130.
DE   RecName: Full=RNA polymerase I-specific transcription initiation factor rrn3;
GN   Name=rrn3; ORFNames=SPAC18G6.11c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Required for efficient transcription initiation by RNA
CC       polymerase I. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRN3 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAA92389.1; -; Genomic_DNA.
DR   PIR; T37924; T37924.
DR   RefSeq; NP_593674.1; NM_001019106.2.
DR   AlphaFoldDB; Q10110; -.
DR   SMR; Q10110; -.
DR   BioGRID; 278969; 3.
DR   STRING; 4896.SPAC18G6.11c.1; -.
DR   MaxQB; Q10110; -.
DR   PaxDb; Q10110; -.
DR   EnsemblFungi; SPAC18G6.11c.1; SPAC18G6.11c.1:pep; SPAC18G6.11c.
DR   PomBase; SPAC18G6.11c; rrn3.
DR   VEuPathDB; FungiDB:SPAC18G6.11c; -.
DR   eggNOG; KOG2434; Eukaryota.
DR   HOGENOM; CLU_010579_0_0_1; -.
DR   InParanoid; Q10110; -.
DR   OMA; VCSPAIV; -.
DR   PhylomeDB; Q10110; -.
DR   Reactome; R-SPO-73762; RNA Polymerase I Transcription Initiation.
DR   Reactome; R-SPO-73772; RNA Polymerase I Promoter Escape.
DR   PRO; PR:Q10110; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000120; C:RNA polymerase I transcription regulator complex; IC:PomBase.
DR   GO; GO:0001042; F:RNA polymerase I core binding; IBA:GO_Central.
DR   GO; GO:0001181; F:RNA polymerase I general transcription initiation factor activity; IDA:PomBase.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; IMP:PomBase.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR007991; RNA_pol_I_trans_ini_fac_RRN3.
DR   PANTHER; PTHR12790; PTHR12790; 1.
DR   Pfam; PF05327; RRN3; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..599
FT                   /note="RNA polymerase I-specific transcription initiation
FT                   factor rrn3"
FT                   /id="PRO_0000211429"
FT   REGION          577..599
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   599 AA;  68555 MW;  8351E6612CE768EF CRC64;
     MPSIISSTNP QYINKCVNNG TMASSTNVPD RTVGSKSFAS SVSKNDGRLM QQMLRAFVNK
     ALDDKAEGNF AGYEDLRRQF AAKSDTKDAP SSLQLQNLLS ALTCNVSRLD SSNSSLVMSV
     LDSVWVSRDE SFVRCYTRFL GNLISAQSNY LPLVMTMLIQ HMLYRPDSLA IHYEHAHMAL
     KYVLELVPRA HSFLYSSILE EFPYKDESLL AQMTYISNVL SICEYVPSIK GPVLHAIIDK
     IIQIDVEIQV EVDDDDEEED EVVTDDDGTS NADSEVITAS TLYERHTAIS SEMTSSTILT
     PPSLTDTRQL MQQLDQLLYT LFSYLDSNLK STSRDRYLVY NSLIKSFVNT VLKTFRCRYT
     QFLIFWASQL DPEFTDIFLG VLTEVCLDPS QPYTLRLSGA MYIGSYVARA KALEKNTIQI
     IVNMMTRWVE AYLDQCENEL SDDLLSKHSV FYAINQSIFY IFCFRWRELC VSDESESMEP
     RPNEWIPGLE ILHRSVLSRL NPLRYCSPNI VLQFAKVANH LNFMYVYSII EQNRKGIFRE
     GFDTMDAYFP FDPYRLTKSS IIVQPFYNEW QQIPGLDDDE EEEDTDYESS TVMLGESPF