ID   RRP12_CHICK             Reviewed;        1294 AA.
AC   Q5ZKD5;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=RRP12-like protein;
GN   Name=RRP12; ORFNames=RCJMB04_11j1;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}. Nucleus
CC       membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRP12 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ720149; CAG31808.1; -; mRNA.
DR   RefSeq; NP_001012926.1; NM_001012908.1.
DR   AlphaFoldDB; Q5ZKD5; -.
DR   STRING; 9031.ENSGALP00000012282; -.
DR   PaxDb; Q5ZKD5; -.
DR   GeneID; 423845; -.
DR   KEGG; gga:423845; -.
DR   CTD; 23223; -.
DR   VEuPathDB; HostDB:geneid_423845; -.
DR   eggNOG; KOG1248; Eukaryota.
DR   InParanoid; Q5ZKD5; -.
DR   OrthoDB; 833555at2759; -.
DR   PhylomeDB; Q5ZKD5; -.
DR   PRO; PR:Q5ZKD5; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR012978; Uncharacterised_NUC173.
DR   Pfam; PF08161; NUC173; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..1294
FT                   /note="RRP12-like protein"
FT                   /id="PRO_0000050770"
FT   TRANSMEM        905..925
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          66..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1049..1144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1178..1225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1255..1294
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1049..1068
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1178..1198
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1294 AA;  144053 MW;  D9F0BAB705FAA92F CRC64;
     MARCGRLRAG TAAKLRRWRK GHSSDCNPET RRHRLAARSR FYSRPTEKSN LTVDAVKLHN
     ELQSGSLRVE RPSGSSQLPM EEGDAGEAAT ERSSGTFLSG LSDCTNVTFS RVQRFWESNS
     AAHKEICAVL AAVTDVIRSQ GGKETETEYF AALMTTLEAV DSPESVAAVA YLLNLVLKRV
     PSPVLIKKFS DASKAFMNII SSQACSGSTS ALRWVLSCLA TLLRKQDLAA WSYPVTLQVY
     HGLLSFCVHT KPKVRKAAQH GVCSVLRGSE FMFGDEAPEH HPAAPSSAKF CVQEIEKAGG
     TKEATTTLHV LALLRDLLPC FPAAVLKTCC ETLLRVMTLS HVLVTACAMQ AFHSLFSAQP
     RTSCLPAELN AQIITALYDY VPSANDLQPL LTWLTTMERA HVNLGRLQKD LCWAHLPRLF
     SATMNCFLSP HLQVVAAAAQ TLETLLNECI APHMDELGNV SASTPAPGSY LCKMFRSVEE
     GLTYRFHAAW DGVLQVLEVF FEVCGKQCHP IMRKCLQSLC DLRLSPHFPY TTEVDQAVGA
     AVGAMGPEVL LEAVPLQIDG KEETLDFPRS WLLPVLRDYV QGARLGFFTS YFLPLAATLK
     SRALEFAQAG KSLESKIYDT LQWQVWTLLP GFCTRPTDVV EAFKGLARTL GMAISERPDL
     RPTVCQALRT LIHHGCGTDA ERAEVGRFAK NFLPILFNVY SQPEEDGGSS SQRRSVLDTV
     RAYLTITDPQ LGCGFLQKAS EKLTSPESSE FARLSILDLV VAMSPYANEQ ALGSLYRTIQ
     PSLQSKDHSM QKKAYRVLEE VCAAPHAPCQ AFVHSHLEEL QAVLLDSLKS AASPAKRPRL
     KCLFHIMKQL SAEHEPFVTA LVPEVILCTK EVSVGARKNA FMLLVEMGHA FIRFGPTPQE
     AMERFLLLVY AGLTGSVTMI SCTVLALTRL FFEFRDHMEL NVVEQLLQNI CLLLGSRTRD
     VVKAALGFIK VVLLLVDTTL LAKHVQTMLE AVGSLSDDMR RHFRMKLRNL FTKFIRKFGF
     ELVQGLLPAE FHKVLVNIRK AEARSRKQRA LRQAAAEAEE EEAPAQPKGD SMEEILADSE
     EEEEEEEERR RGKVRKKQAR QKGQAWLKEG EEDEPLNFLD PNVSQRVLAT EPSLKKSRGV
     KHDFQVSEDG RLIIHDEEEE VDNDEAKGVE EEVADVLQEV GLRSKKSQKR RFREEPDDDE
     PETGTYSQYR AGGSGIHRPL DKKPAFGAEY RSKKGKGDVK KKGQLDPYAY IPLNRAKLNK
     RKQAKMQGQF KGLMKGAQRG AKAGRKNRLK DRRP