ID   RRP36_AJECN             Reviewed;         345 AA.
AC   A6RF22;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=rRNA biogenesis protein RRP36;
DE   AltName: Full=Ribosomal RNA-processing protein 36;
GN   Name=RRP36; ORFNames=HCAG_08237;
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma;
OC   unclassified Histoplasma.
OX   NCBI_TaxID=2059318;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC       of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC       ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR   EMBL; CH476664; EDN04571.1; -; Genomic_DNA.
DR   RefSeq; XP_001537128.1; XM_001537078.1.
DR   AlphaFoldDB; A6RF22; -.
DR   SMR; A6RF22; -.
DR   STRING; 339724.A6RF22; -.
DR   EnsemblFungi; EDN04571; EDN04571; HCAG_08237.
DR   GeneID; 5443329; -.
DR   KEGG; aje:HCAG_08237; -.
DR   VEuPathDB; FungiDB:HCAG_08237; -.
DR   HOGENOM; CLU_048802_0_0_1; -.
DR   OMA; HRTSKHA; -.
DR   OrthoDB; 1471490at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR   InterPro; IPR009292; RRP36.
DR   PANTHER; PTHR21738; PTHR21738; 1.
DR   Pfam; PF06102; RRP36; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; Ribonucleoprotein;
KW   Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..345
FT                   /note="rRNA biogenesis protein RRP36"
FT                   /id="PRO_0000397609"
FT   REGION          15..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          312..345
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          219..267
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        15..46
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        47..62
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        100..134
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        150..165
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   345 AA;  39918 MW;  7A3552E149C1A121 CRC64;
     MPISSKLNQR VRARLREEDF EHFSDESVSN ESLDERESNE DTEQDNRDQR ETDDDDTEDD
     GHTEISDINP SLNTISFGAL AKAQAALGKR KRRTTSTTDI TPKRTKVLSR QSPTPSTSSN
     KEHDQGQGLS EFQKHLASNA KKPPQKLTHR TSKHAPTIQS SRHAVSRKRT IIEPLAAPKP
     RDPRFDSVVL SHSTNGNPST AANADIHARN NYAFLNHYRT DEIAELRKQV SALQTKKKKT
     ERDDHEIVRL KREITSMSDR QRAFERKEME REVLVQHRRR EKELIREGKK SQPYFLKKGE
     VKKEVIAKRF TEMSGKEKQR ALERRRKKVV GKERKEMPWG RRGVE