RRP36_AJEDR
ID RRP36_AJEDR Reviewed; 356 AA.
AC C5GLN0;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=rRNA biogenesis protein RRP36;
DE AltName: Full=Ribosomal RNA-processing protein 36;
GN Name=RRP36; ORFNames=BDCG_05262;
OS Ajellomyces dermatitidis (strain ER-3 / ATCC MYA-2586) (Blastomyces
OS dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=559297;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ER-3 / ATCC MYA-2586;
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR EMBL; EQ999977; EEQ90142.1; -; Genomic_DNA.
DR AlphaFoldDB; C5GLN0; -.
DR STRING; 559297.C5GLN0; -.
DR PRIDE; C5GLN0; -.
DR EnsemblFungi; EEQ90142; EEQ90142; BDCG_05262.
DR VEuPathDB; FungiDB:BDCG_05262; -.
DR eggNOG; KOG3190; Eukaryota.
DR HOGENOM; CLU_048802_0_0_1; -.
DR OMA; HRTSKHA; -.
DR Proteomes; UP000002039; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR InterPro; IPR009292; RRP36.
DR PANTHER; PTHR21738; PTHR21738; 1.
DR Pfam; PF06102; RRP36; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosome biogenesis; rRNA processing.
FT CHAIN 1..356
FT /note="rRNA biogenesis protein RRP36"
FT /id="PRO_0000397610"
FT REGION 1..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 230..278
FT /evidence="ECO:0000255"
FT COMPBIAS 33..74
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 40485 MW; 67FE6A4125D59CD0 CRC64;
MPISSKFNQR VRARLEEDEF EQFSGESTSD EGLEGGESVE DEEEQEENSA EDHSEEDDDE
GEEDDDDDGD VEDSSSDINP SLNAISFGAL AKAQASLGKR KRPTASTGGI SPKRAKVPGR
HSPTPSASSS GEKQEPEPEL SEYQKHLAAN AKKPPQKLTH RTSKHAPTIQ SSRHAVSRKR
TILEPPPVPK ARDPRFDSVV LSHSTNGNSS TASNAAIHAR KNYAFLDSYR KDEIAQLRKQ
VSTLQTKKHK TNYDERELAR LKRQITSMSD RQRTFERKEM EREVLVQHRR KERELIREGK
KSQPYFLKRG EVKKEAVAKR FTEMSGKEKQ RALERRRKKV AGKERKEMPW GRRVVE