RRP36_ARTOC
ID RRP36_ARTOC Reviewed; 365 AA.
AC C5FRS7;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=rRNA biogenesis protein RRP36;
DE AltName: Full=Ribosomal RNA-processing protein 36;
GN Name=RRP36; ORFNames=MCYG_05399;
OS Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Microsporum.
OX NCBI_TaxID=554155;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4605 / CBS 113480;
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR EMBL; DS995705; EEQ32580.1; -; Genomic_DNA.
DR RefSeq; XP_002845530.1; XM_002845484.1.
DR AlphaFoldDB; C5FRS7; -.
DR SMR; C5FRS7; -.
DR STRING; 63405.XP_002845530.1; -.
DR EnsemblFungi; EEQ32580; EEQ32580; MCYG_05399.
DR GeneID; 9228740; -.
DR eggNOG; KOG3190; Eukaryota.
DR HOGENOM; CLU_048802_0_0_1; -.
DR OMA; HRTSKHA; -.
DR OrthoDB; 1471490at2759; -.
DR Proteomes; UP000002035; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR InterPro; IPR009292; RRP36.
DR PANTHER; PTHR21738; PTHR21738; 1.
DR Pfam; PF06102; RRP36; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosome biogenesis; rRNA processing.
FT CHAIN 1..365
FT /note="rRNA biogenesis protein RRP36"
FT /id="PRO_0000397640"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 62..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 103..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 134..162
FT /evidence="ECO:0000255"
FT COILED 242..286
FT /evidence="ECO:0000255"
FT COMPBIAS 128..179
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..365
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 365 AA; 41877 MW; 16BF34320127B5C5 CRC64;
MSLLGKRIRA PREDDDLLDE GLSSSEELNS ASGGDEDGEL EDAETVRVPF LIYDDKELLE
IADLPPIGQS DLEDSPSEKE GENDIESSLS QISFGALAKV QRSLGPLKKG SKRKHRGQEE
EEEEEEQDNG NTKYKKSKLD ALNELRERIR RAKEGKASKS GQSKDEEAAV KKQKESRLSK
HAPAIQSSKF AVSRRRVVVD GENVAQVKSR DPRFDSAVQS YSHSHRLGSH SDPAAAKNYA
FLNDYRDAEL KELEEKLRRA KNEDEKQQLK KTITSMNDRK RALEHRDRER QILSKHRKRE
RELIKEGKKE KAWFLKKADL KKEALKEKYE SMGAKQRQKG IERRRKKVAS KEKKEMPRSR
RMVEG