RRP36_BLAGS
ID RRP36_BLAGS Reviewed; 356 AA.
AC C5JYW1; A0A179UYU2;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 38.
DE RecName: Full=rRNA biogenesis protein RRP36;
DE AltName: Full=Ribosomal RNA-processing protein 36;
GN Name=RRP36; ORFNames=BDBG_07734;
OS Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=559298;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SLH14081;
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR EMBL; GG657467; OAT12389.1; -; Genomic_DNA.
DR RefSeq; XP_002621895.1; XM_002621849.1.
DR AlphaFoldDB; C5JYW1; -.
DR STRING; 559298.C5JYW1; -.
DR EnsemblFungi; OAT12389; OAT12389; BDBG_07734.
DR GeneID; 8502162; -.
DR KEGG; bgh:BDBG_07734; -.
DR VEuPathDB; FungiDB:BDBG_07734; -.
DR HOGENOM; CLU_048802_0_0_1; -.
DR Proteomes; UP000002038; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR InterPro; IPR009292; RRP36.
DR PANTHER; PTHR21738; PTHR21738; 1.
DR Pfam; PF06102; RRP36; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosome biogenesis; rRNA processing.
FT CHAIN 1..356
FT /note="rRNA biogenesis protein RRP36"
FT /id="PRO_0000397611"
FT REGION 1..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 230..278
FT /evidence="ECO:0000255"
FT COMPBIAS 33..74
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 40486 MW; 78A06F09A80443C4 CRC64;
MPISSKFNQR VRARLEEDEF EQFSGESTSD EGLEGGESVE DEEEEEENSA EDHSEEDDDE
GEEDDDDDGD VEDSSSDINP SLNAISFGAL AKAQASLGKR KRPTASTGGI SPKRAKVPGR
HSPTPSASSS GEKQEPEPEL SEYQKHLAAN AKKPPQKLTH RTSKHAPTIQ SSRHAVSRKR
TILEPPPVPK ARDPRFDSVV LSHSTNGNSS TASNAAIHAR KNYAFLDSYR KDEIAQLRKQ
VSTLQTKKHK TNYDERELAR LKRQITSMSD RQRTFERKEM EREVLVQHRR KERELIREGK
KSKPYFLKRG EVKKEAVAKR FTEMSGKEKQ RALERRRKKV AGKERKEMPW GRRVVE