RRP36_CANAW
ID RRP36_CANAW Reviewed; 281 AA.
AC C4YMC1;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 44.
DE RecName: Full=rRNA biogenesis protein RRP36;
DE AltName: Full=Ribosomal RNA-processing protein 36;
GN Name=RRP36; ORFNames=CAWG_02000;
OS Candida albicans (strain WO-1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294748;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WO-1;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM000309; EEQ43752.1; -; Genomic_DNA.
DR AlphaFoldDB; C4YMC1; -.
DR SMR; C4YMC1; -.
DR STRING; 5476.C4YMC1; -.
DR EnsemblFungi; EEQ43752; EEQ43752; CAWG_02000.
DR VEuPathDB; FungiDB:CAWG_02000; -.
DR HOGENOM; CLU_048802_3_0_1; -.
DR OMA; HRTSKHA; -.
DR Proteomes; UP000001429; Chromosome R.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR InterPro; IPR009292; RRP36.
DR PANTHER; PTHR21738; PTHR21738; 1.
DR Pfam; PF06102; RRP36; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Ribonucleoprotein; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..281
FT /note="rRNA biogenesis protein RRP36"
FT /id="PRO_0000397622"
FT REGION 1..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 243..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 48..78
FT /evidence="ECO:0000255"
FT COILED 161..205
FT /evidence="ECO:0000255"
FT COMPBIAS 8..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..79
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 281 AA; 32926 MW; 0CE2EC1B0C1EF9EB CRC64;
MSRGKTIRPS YYDEEESSQD ELSHTLNKGR SNIGSQSDDE EMSKISFGAL NRAQTKLNKH
NQKHKTQEDN YKSSEEEFFD SGSDSDGLPE ETSSKDTKKK KNKHAPSESS SKRPVSRIRD
IPGLPSRKQQ TLHTDIRFDA AYGKADLAKA RKDYAFLDEY RKQEIANMES LLKDKKSKLN
DDEREEIKLQ LQSLKSRMDT LKNRDLENSI LSNYKKQQME SFKEGKVNKP YFLKRSDKRK
ILQKAKFDSM KPKQREKAME RKRKKRLGKE FRQLEFKPTN R