RRP36_CANDC
ID RRP36_CANDC Reviewed; 285 AA.
AC B9WMA4;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 48.
DE RecName: Full=rRNA biogenesis protein RRP36;
DE AltName: Full=Ribosomal RNA-processing protein 36;
GN Name=RRP36; ORFNames=CD36_32570;
OS Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 /
OS NRRL Y-17841) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=573826;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841;
RX PubMed=19745113; DOI=10.1101/gr.097501.109;
RA Jackson A.P., Gamble J.A., Yeomans T., Moran G.P., Saunders D., Harris D.,
RA Aslett M., Barrell J.F., Butler G., Citiulo F., Coleman D.C.,
RA de Groot P.W.J., Goodwin T.J., Quail M.A., McQuillan J., Munro C.A.,
RA Pain A., Poulter R.T., Rajandream M.A., Renauld H., Spiering M.J.,
RA Tivey A., Gow N.A.R., Barrell B., Sullivan D.J., Berriman M.;
RT "Comparative genomics of the fungal pathogens Candida dubliniensis and
RT Candida albicans.";
RL Genome Res. 19:2231-2244(2009).
CC -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR EMBL; FM992695; CAX40217.1; -; Genomic_DNA.
DR RefSeq; XP_002422213.1; XM_002422168.1.
DR AlphaFoldDB; B9WMA4; -.
DR STRING; 42374.XP_002422213.1; -.
DR EnsemblFungi; CAX40217; CAX40217; CD36_32570.
DR GeneID; 8049362; -.
DR KEGG; cdu:CD36_32570; -.
DR CGD; CAL0000159549; Cd36_32570.
DR VEuPathDB; FungiDB:CD36_32570; -.
DR eggNOG; KOG3190; Eukaryota.
DR HOGENOM; CLU_048802_3_0_1; -.
DR OrthoDB; 1471490at2759; -.
DR Proteomes; UP000002605; Chromosome R.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR InterPro; IPR009292; RRP36.
DR PANTHER; PTHR21738; PTHR21738; 1.
DR Pfam; PF06102; RRP36; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Ribonucleoprotein; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..285
FT /note="rRNA biogenesis protein RRP36"
FT /id="PRO_0000397624"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 26..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 165..209
FT /evidence="ECO:0000255"
FT COMPBIAS 50..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..119
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 285 AA; 33432 MW; 23B4B5A03BCC2D10 CRC64;
MSRGKTIRPS YYDEDESSQD ELEYTLNKGR SNIGSESDSD VDEMSKISFG ALNRAQTKLN
KNNQKHKPSS WKENINNSSE EFFDSDSDSD GPPEETSSKD TKKKKNKHAP SESSSKRPVS
RIRDIPGLPS RKQQTLHTDI RFDAAYGKAD LIKARKDYAF LDEYRKQEIA SMESLLKDKK
NKLNDDEREE IKLQLQSLKS RMDTLKNRDL ENNILSNYKK QQMESFKEGK VNKPYFLKRS
DKRKILQKAK FDSMKPKQRE KAMERKRKKR LGKEFRQLEF RPTNR
