RRP36_CLAL4
ID RRP36_CLAL4 Reviewed; 278 AA.
AC C4Y4A0;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 39.
DE RecName: Full=rRNA biogenesis protein RRP36;
DE AltName: Full=Ribosomal RNA-processing protein 36;
GN Name=RRP36; ORFNames=CLUG_02472;
OS Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Clavispora.
OX NCBI_TaxID=306902;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42720;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR EMBL; CH408078; EEQ38346.1; -; Genomic_DNA.
DR RefSeq; XP_002617028.1; XM_002616982.1.
DR AlphaFoldDB; C4Y4A0; -.
DR SMR; C4Y4A0; -.
DR STRING; 306902.C4Y4A0; -.
DR EnsemblFungi; EEQ38346; EEQ38346; CLUG_02472.
DR GeneID; 8498083; -.
DR KEGG; clu:CLUG_02472; -.
DR VEuPathDB; FungiDB:CLUG_02472; -.
DR HOGENOM; CLU_048802_3_0_1; -.
DR InParanoid; C4Y4A0; -.
DR OMA; HRTSKHA; -.
DR Proteomes; UP000007703; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR InterPro; IPR009292; RRP36.
DR PANTHER; PTHR21738; PTHR21738; 1.
DR Pfam; PF06102; RRP36; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosome biogenesis; rRNA processing.
FT CHAIN 1..278
FT /note="rRNA biogenesis protein RRP36"
FT /id="PRO_0000397628"
FT REGION 1..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 165..204
FT /evidence="ECO:0000255"
FT COMPBIAS 1..34
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 278 AA; 32792 MW; E47810A41A1109BA CRC64;
MSTHRFKPSY DESESEDDYL GSVLDNKDES DDDFSSLSFG ALNSAQKKLR EQSETQRPPS
RKSSKNQESD DSDSDSDDQF FEDKKSKKTK DKKSKRSKHA PAEASFKRPV PKIREIPGLK
SAKDSTLYTD IRFDAAYGKA DLNRVRKDYA FLDELRQKEI AEMKAVLKND KLRRKMSQRE
IEDLELQVKS LQSRLDTLKN RDLSTKIISD HKKQQMEKMK KGEQVNPYYL KKSEQRKMIQ
KAKFETMKAS QREKVMERKR KRKLGREFRQ LEFREPQR