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RRP36_COCP7
ID   RRP36_COCP7             Reviewed;         333 AA.
AC   C5P263;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=rRNA biogenesis protein RRP36;
DE   AltName: Full=Ribosomal RNA-processing protein 36;
GN   Name=RRP36; ORFNames=CPC735_036720;
OS   Coccidioides posadasii (strain C735) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=222929;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C735;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC       of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC       ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR   EMBL; ACFW01000012; EER28966.1; -; Genomic_DNA.
DR   RefSeq; XP_003071111.1; XM_003071065.1.
DR   AlphaFoldDB; C5P263; -.
DR   SMR; C5P263; -.
DR   EnsemblFungi; EER28966; EER28966; CPC735_036720.
DR   GeneID; 9696606; -.
DR   KEGG; cpw:CPC735_036720; -.
DR   VEuPathDB; FungiDB:CPC735_036720; -.
DR   HOGENOM; CLU_048802_0_0_1; -.
DR   Proteomes; UP000009084; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR   InterPro; IPR009292; RRP36.
DR   PANTHER; PTHR21738; PTHR21738; 1.
DR   Pfam; PF06102; RRP36; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..333
FT                   /note="rRNA biogenesis protein RRP36"
FT                   /id="PRO_0000397629"
FT   REGION          1..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          84..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          303..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          218..259
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        20..62
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..148
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   333 AA;  37215 MW;  3493D850CB820581 CRC64;
     MALLDSLNRR IKARVDDDDP EEYSDLSSSE QDGSDADSDE LEGSEAASDG GSDDEELSDS
     SAPEDTAIDA SLNQISFGAL AKAQASLGLS SSSSNNRRKR KLSTDKEQGP SPLDDIRARI
     RATREEKSKS TASTTTSKDK KDLPHRSSKH APTVQSSKHA VSRKRTVVDA TAISGPKARD
     PRFDSVVLSH GTSNPQALGN AQAAAAKNYS FLNDYRDAEL SSLKQQLAKA KNPAEKEQLK
     RTIRSMTDKI RTFERKQREK EVVARHRRRE RDLIREGKKS TPYFLKKGDV KKEVLKQRYE
     EMGAKDRQKS IVRRRKKVAA RERREMPDMR RTG
 
 
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