RRP36_COCP7
ID RRP36_COCP7 Reviewed; 333 AA.
AC C5P263;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-SEP-2009, sequence version 1.
DT 25-MAY-2022, entry version 41.
DE RecName: Full=rRNA biogenesis protein RRP36;
DE AltName: Full=Ribosomal RNA-processing protein 36;
GN Name=RRP36; ORFNames=CPC735_036720;
OS Coccidioides posadasii (strain C735) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=222929;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C735;
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR EMBL; ACFW01000012; EER28966.1; -; Genomic_DNA.
DR RefSeq; XP_003071111.1; XM_003071065.1.
DR AlphaFoldDB; C5P263; -.
DR SMR; C5P263; -.
DR EnsemblFungi; EER28966; EER28966; CPC735_036720.
DR GeneID; 9696606; -.
DR KEGG; cpw:CPC735_036720; -.
DR VEuPathDB; FungiDB:CPC735_036720; -.
DR HOGENOM; CLU_048802_0_0_1; -.
DR Proteomes; UP000009084; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR InterPro; IPR009292; RRP36.
DR PANTHER; PTHR21738; PTHR21738; 1.
DR Pfam; PF06102; RRP36; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Ribonucleoprotein; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..333
FT /note="rRNA biogenesis protein RRP36"
FT /id="PRO_0000397629"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 84..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 303..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 218..259
FT /evidence="ECO:0000255"
FT COMPBIAS 20..62
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..148
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 333 AA; 37215 MW; 3493D850CB820581 CRC64;
MALLDSLNRR IKARVDDDDP EEYSDLSSSE QDGSDADSDE LEGSEAASDG GSDDEELSDS
SAPEDTAIDA SLNQISFGAL AKAQASLGLS SSSSNNRRKR KLSTDKEQGP SPLDDIRARI
RATREEKSKS TASTTTSKDK KDLPHRSSKH APTVQSSKHA VSRKRTVVDA TAISGPKARD
PRFDSVVLSH GTSNPQALGN AQAAAAKNYS FLNDYRDAEL SSLKQQLAKA KNPAEKEQLK
RTIRSMTDKI RTFERKQREK EVVARHRRRE RDLIREGKKS TPYFLKKGDV KKEVLKQRYE
EMGAKDRQKS IVRRRKKVAA RERREMPDMR RTG