ID   RRP36_CRYNJ             Reviewed;         296 AA.
AC   P0CR20; Q55PM8; Q5KDS8;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=rRNA biogenesis protein RRP36;
DE   AltName: Full=Ribosomal RNA-processing protein 36;
GN   Name=RRP36; OrderedLocusNames=CNG02910;
OS   Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS   MYA-565) (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=214684;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEC21 / ATCC MYA-565;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC       of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC       ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR   EMBL; AE017347; AAW44672.1; -; Genomic_DNA.
DR   RefSeq; XP_571979.1; XM_571979.1.
DR   AlphaFoldDB; P0CR20; -.
DR   STRING; 5207.AAW44672; -.
DR   PaxDb; P0CR20; -.
DR   eggNOG; KOG3190; Eukaryota.
DR   HOGENOM; CLU_048802_1_1_1; -.
DR   InParanoid; P0CR20; -.
DR   OMA; HRTSKHA; -.
DR   OrthoDB; 1188249at2759; -.
DR   Proteomes; UP000002149; Chromosome 7.
DR   GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   InterPro; IPR009292; RRP36.
DR   PANTHER; PTHR21738; PTHR21738; 1.
DR   Pfam; PF06102; RRP36; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; Ribonucleoprotein;
KW   Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..296
FT                   /note="rRNA biogenesis protein RRP36"
FT                   /id="PRO_0000397631"
FT   REGION          15..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          253..296
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          147..203
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        15..34
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..124
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        260..274
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        275..296
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   296 AA;  33125 MW;  BB28BE77E77ECA32 CRC64;
     MFADLNSLPL STLAKAQKSL SRKSSSSSSN GRSKEEKLAL MKSKLAQMQR SKGKAVAVPD
     TDSHRFGSRA QESDEESDSG PETTSSTKRG SKHAPAALST KKQVSRKRQV IEVPKPERRD
     PRFSSVSAGH ANADLHSKSY SFLPDLLRQE FSGLKEAVAA AKKAEKNCPW AEKPMRTAER
     ERLEVQMGQV RTKLVRTEKE AMEREVLAKA KKEEREKRTQ GKAAWFMKKG ESPKCEKKDL
     LLKARFETLE KQGGKTAVKK LVEKKRKKLA SKEKKSRPFA KGAEGMGRDT KRRRVA