ID   RRP36_DICDI             Reviewed;         298 AA.
AC   Q54XT8;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Ribosomal RNA processing protein 36 homolog;
GN   ORFNames=DDB_G0278751;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Involved in the early processing steps of the pre-rRNA in the
CC       maturation pathway leading to the 18S rRNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR   EMBL; AAFI02000024; EAL67977.1; -; Genomic_DNA.
DR   RefSeq; XP_641913.1; XM_636821.1.
DR   AlphaFoldDB; Q54XT8; -.
DR   STRING; 44689.DDB0206170; -.
DR   PaxDb; Q54XT8; -.
DR   EnsemblProtists; EAL67977; EAL67977; DDB_G0278751.
DR   GeneID; 8621674; -.
DR   KEGG; ddi:DDB_G0278751; -.
DR   dictyBase; DDB_G0278751; -.
DR   eggNOG; KOG3190; Eukaryota.
DR   HOGENOM; CLU_048802_0_0_1; -.
DR   InParanoid; Q54XT8; -.
DR   OMA; HRTSKHA; -.
DR   PhylomeDB; Q54XT8; -.
DR   Reactome; R-DDI-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   PRO; PR:Q54XT8; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   InterPro; IPR009292; RRP36.
DR   PANTHER; PTHR21738; PTHR21738; 1.
DR   Pfam; PF06102; RRP36; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..298
FT                   /note="Ribosomal RNA processing protein 36 homolog"
FT                   /id="PRO_0000338397"
FT   REGION          1..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          279..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          88..112
FT                   /evidence="ECO:0000255"
FT   COILED          196..228
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..57
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        60..94
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        95..125
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   298 AA;  35887 MW;  308622973E5C8FEB CRC64;
     MKPDIIKKRR PLPSDDEDEY NEEDEMYEDD NNNYEEDEDD DDDDDEDDED DDENEEELIK
     QQLSNVSFSS LLKYKKNGPT DKLNLNTITK NLQQQKSFKK EEQQEKEEMN SKNKYKIKRE
     SSDAPVEMTA MKPVSRFRQV VVNKTKMNVR DPRFDSLSGG KYNEDLYRKR YGFLDDVIKR
     DVERMESTWK QMDDCRERDQ LYKKIQSKKS QLKTQQLKDQ KRETKNKLWS NEIESVKKGK
     TPYHISNKTV KQFELQEKFK QLKASNKLDK FMETKRKRIS SKEKTFLPQR RSFDQDEN