RRP36_KOMPG
ID RRP36_KOMPG Reviewed; 289 AA.
AC C4QVB0;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 07-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 51.
DE RecName: Full=rRNA biogenesis protein RRP36;
DE AltName: Full=Ribosomal RNA-processing protein 36;
GN Name=RRP36; OrderedLocusNames=PAS_chr1-3_0123;
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864;
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR EMBL; FN392319; CAY67183.1; -; Genomic_DNA.
DR RefSeq; XP_002489464.1; XM_002489419.1.
DR AlphaFoldDB; C4QVB0; -.
DR STRING; 644223.C4QVB0; -.
DR PRIDE; C4QVB0; -.
DR EnsemblFungi; CAY67183; CAY67183; PAS_chr1-3_0123.
DR GeneID; 8197591; -.
DR KEGG; ppa:PAS_chr1-3_0123; -.
DR eggNOG; KOG3190; Eukaryota.
DR HOGENOM; CLU_048802_3_0_1; -.
DR InParanoid; C4QVB0; -.
DR OMA; HRTSKHA; -.
DR Proteomes; UP000000314; Chromosome 1.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR InterPro; IPR009292; RRP36.
DR PANTHER; PTHR21738; PTHR21738; 1.
DR Pfam; PF06102; RRP36; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosome biogenesis; rRNA processing.
FT CHAIN 1..289
FT /note="rRNA biogenesis protein RRP36"
FT /id="PRO_0000397651"
FT REGION 27..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 253..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 162..224
FT /evidence="ECO:0000255"
FT COMPBIAS 39..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..136
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 289 AA; 34013 MW; 68B7F79B58898CA9 CRC64;
MKAQKFSKAS LLDDEDDYST QLDRILARRK KSQKEDSGDL DTISFGSLSK AQARLQTEER
ESKKKVKKVK KPKVLKKQEE DFQPPSDISD DGEFFEEPSQ DHQSRTSDRH SKEEPRSKSK
HAPSESSAKK RVSKVREIPG LLNGSGSSSL YQDVRFDTAF GKADLQKARE NYKFLDEYRE
KEITELNKIL QDDMTEQLLS EREINTIKYK IQSLKSRVDT LKNRDLENEI VRDYKRNHKN
FFLKNSDKRK LVQKAKFDSM KPSQREKVIE RKRKRQLGRE FKQLEFNQK