RRP36_LACTC
ID RRP36_LACTC Reviewed; 317 AA.
AC C5DF79;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 57.
DE RecName: Full=rRNA biogenesis protein RRP36;
DE AltName: Full=Ribosomal RNA-processing protein 36;
GN Name=RRP36; OrderedLocusNames=KLTH0D12892g;
OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS (Yeast) (Kluyveromyces thermotolerans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=559295;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR EMBL; CU928168; CAR22834.1; -; Genomic_DNA.
DR RefSeq; XP_002553272.1; XM_002553226.1.
DR AlphaFoldDB; C5DF79; -.
DR SMR; C5DF79; -.
DR STRING; 559295.C5DF79; -.
DR EnsemblFungi; CAR22834; CAR22834; KLTH0D12892g.
DR GeneID; 8295512; -.
DR KEGG; lth:KLTH0D12892g; -.
DR eggNOG; KOG3190; Eukaryota.
DR HOGENOM; CLU_048802_3_0_1; -.
DR InParanoid; C5DF79; -.
DR OMA; HRTSKHA; -.
DR OrthoDB; 1471490at2759; -.
DR Proteomes; UP000002036; Chromosome D.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR InterPro; IPR009292; RRP36.
DR PANTHER; PTHR21738; PTHR21738; 1.
DR Pfam; PF06102; RRP36; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosome biogenesis; rRNA processing.
FT CHAIN 1..317
FT /note="rRNA biogenesis protein RRP36"
FT /id="PRO_0000397636"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 54..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 220..248
FT /evidence="ECO:0000255"
FT COMPBIAS 54..96
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 317 AA; 37666 MW; 21E2F971771DCD50 CRC64;
MSYYFKNLKP GYESDEELED DEILKTLSKR YADEDESASD DELSSLSFDA LRRAERQLEE
ESRKEKAGSQ NESKPALKNA KRSKEKELEL ADSFKAKSYT EESFGENSDS SSENEGLFEE
EEVVRGNKNS KADHGKNRKK SHAPSEQSSK KKVSRIRKIP GLETPKSMNE NLYQDIRFDK
SLGKAEDYES IRKRYQFLDE YRQKEISELS RLLSDRKFVN KISERERDEM QEKLTSMRSK
LQTLKNRDLD RKILKDYETE INKGNKTKYH LKESEKRKVI QKYKFDHMKA KQREKVMDRK
RKKRLGKEFK QFSFHNR