RRP36_PICST
ID RRP36_PICST Reviewed; 291 AA.
AC A3LP95;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 2.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=rRNA biogenesis protein RRP36;
DE AltName: Full=Ribosomal RNA-processing protein 36;
GN Name=RRP36; ORFNames=PICST_35049;
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR EMBL; CP000496; ABN65002.2; -; Genomic_DNA.
DR RefSeq; XP_001383031.2; XM_001382994.1.
DR AlphaFoldDB; A3LP95; -.
DR SMR; A3LP95; -.
DR STRING; 4924.XP_001383031.2; -.
DR EnsemblFungi; ABN65002; ABN65002; PICST_35049.
DR GeneID; 4836913; -.
DR KEGG; pic:PICST_35049; -.
DR eggNOG; KOG3190; Eukaryota.
DR HOGENOM; CLU_048802_3_0_1; -.
DR InParanoid; A3LP95; -.
DR OMA; HRTSKHA; -.
DR OrthoDB; 1471490at2759; -.
DR Proteomes; UP000002258; Chromosome 2.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR InterPro; IPR009292; RRP36.
DR PANTHER; PTHR21738; PTHR21738; 1.
DR Pfam; PF06102; RRP36; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosome biogenesis; rRNA processing.
FT CHAIN 1..291
FT /note="rRNA biogenesis protein RRP36"
FT /id="PRO_0000397652"
FT REGION 1..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 188..215
FT /evidence="ECO:0000255"
FT COMPBIAS 70..85
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..191
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 291 AA; 34089 MW; C3BDA604B2D4B4D8 CRC64;
MRPSYNDDGF SDDEFTNSIL TKRDEQDDSL ESMTFGALNS AQNELLGKKK KKKSIQTESK
KRKYSESESE EDSEDSEEES DSDSDAPPQE NSSRGKTSRF QKNGEKKKRS KHAPAETSSK
KPVSRIREIP GLKSSKESTL YTDIRFDPAY GKADLRKTRK DYAFLDEYRQ SEVKSMETML
KDKKSGQMLS NRDREEIQLQ LQSLKSRLDT MKNRDLEEKI LADHKRNQIK GFKDGQQNNP
YFLKRSDKRK LIQKAKFDSM KASQREKVME RKRKKRLGKE FRQLEFNQPR H