RRP36_SCHPO
ID RRP36_SCHPO Reviewed; 265 AA.
AC Q9P6P2;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 22-FEB-2012, sequence version 3.
DT 25-MAY-2022, entry version 100.
DE RecName: Full=rRNA biogenesis protein rrp36;
DE AltName: Full=Ribosomal RNA-processing protein 36;
GN Name=rrp36; ORFNames=SPAC823.04;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP REVISION OF GENE MODEL, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=21270388; DOI=10.1534/genetics.110.123497;
RA Bitton D.A., Wood V., Scutt P.J., Grallert A., Yates T., Smith D.L.,
RA Hagan I.M., Miller C.J.;
RT "Augmented annotation of the Schizosaccharomyces pombe genome reveals
RT additional genes required for growth and viability.";
RL Genetics 187:1207-1217(2011).
CC -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR EMBL; CU329670; CAB90149.3; -; Genomic_DNA.
DR RefSeq; NP_593831.3; NM_001019260.3.
DR AlphaFoldDB; Q9P6P2; -.
DR SMR; Q9P6P2; -.
DR BioGRID; 279825; 1.
DR STRING; 4896.SPAC823.04.1; -.
DR MaxQB; Q9P6P2; -.
DR PaxDb; Q9P6P2; -.
DR EnsemblFungi; SPAC823.04.1; SPAC823.04.1:pep; SPAC823.04.
DR GeneID; 2543403; -.
DR KEGG; spo:SPAC823.04; -.
DR PomBase; SPAC823.04; rrp36.
DR VEuPathDB; FungiDB:SPAC823.04; -.
DR eggNOG; KOG3190; Eukaryota.
DR HOGENOM; CLU_048802_4_2_1; -.
DR InParanoid; Q9P6P2; -.
DR Reactome; R-SPO-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR PRO; PR:Q9P6P2; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0030686; C:90S preribosome; ISO:PomBase.
DR GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0000469; P:cleavage involved in rRNA processing; ISO:PomBase.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISO:PomBase.
DR InterPro; IPR009292; RRP36.
DR PANTHER; PTHR21738; PTHR21738; 1.
DR Pfam; PF06102; RRP36; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosome biogenesis; rRNA processing.
FT CHAIN 1..265
FT /note="rRNA biogenesis protein rrp36"
FT /id="PRO_0000339880"
FT REGION 1..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 146..204
FT /evidence="ECO:0000255"
FT COMPBIAS 18..47
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 265 AA; 31342 MW; C5AD17F3149A92E4 CRC64;
MKSSSLENGT LANAGVYEDD LDSDEELVSE EEFENFNNED SEDDEDSNNE SKTAKSQLAE
IPFDTLLNAQ RDLLKEQQKT KIDRKNMKHT EKVDKKFLAK ERNTPLKNCQ VKNQFLVFAK
FDSLSGNLSK DKVKKNYGFL NEYRVSEIQQ LRDELKICKD QERAESIRQT LKSLLSKMER
HLEEERAERV MHEFRAQEKE RVKEGKKPFY LKRNEQKKLI QMDKYKSMEG TKALDKYIEK
KRRRRAQKEK KHLPRARPSA NSQNK
