ID   RRP36_YEAS7             Reviewed;         300 AA.
AC   A6ZPC2;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=rRNA biogenesis protein RRP36;
DE   AltName: Full=Ribosomal RNA-processing protein 36;
GN   Name=RRP36; ORFNames=SCY_5337;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC       of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC       ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC       Interacts with CKA1, CKA2, CKB1, CKB2, PWP2, UTP15, UTP17 and UTP22 (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
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DR   EMBL; AAFW02000032; EDN63612.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZPC2; -.
DR   SMR; A6ZPC2; -.
DR   PRIDE; A6ZPC2; -.
DR   EnsemblFungi; EDN63612; EDN63612; SCY_5337.
DR   HOGENOM; CLU_048802_3_0_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR   InterPro; IPR009292; RRP36.
DR   PANTHER; PTHR21738; PTHR21738; 1.
DR   Pfam; PF06102; RRP36; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Phosphoprotein; Ribonucleoprotein;
KW   Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..300
FT                   /note="rRNA biogenesis protein RRP36"
FT                   /id="PRO_0000397659"
FT   REGION          33..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          203..248
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        33..83
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        84..105
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        106..139
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         14
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q12481"
FT   MOD_RES         41
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q12481"
FT   MOD_RES         42
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q12481"
SQ   SEQUENCE   300 AA;  36170 MW;  F84EA87FB61F46FC CRC64;
     MSYYFKNLKP DLNSDVEEDD GNLLESIMAN KSKREIDEQE SSDDELKTLS FGSLKKAETV
     IDEEDFKDTK PVHKKPITTT YREESFDEDE DSEDQSDEDA GFFEEDSEDE THHGQKVPKK
     KSKHAPVEQS SKKRVPRVRN IPGLEIPRNK RSNLYRDIRF DKSTGKALDS SIIRKRYQFL
     DEYREKEIDE LQKLLQDRKF LSKIDQGERE EMEQRLKSMK SRLQSMKNKD LEREILKEYE
     NDMNKNNNTR YHLKKSEKRK VVQKWKFDHM KTKQREKVME RKRKKRLGKE FKQFEFHNRR