ID   RRP36_YEAS8             Reviewed;         300 AA.
AC   C8ZH37;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=rRNA biogenesis protein RRP36;
DE   AltName: Full=Ribosomal RNA-processing protein 36;
GN   Name=RRP36; ORFNames=EC1118_1O4_5193g;
OS   Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS   yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=643680;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lalvin EC1118 / Prise de mousse;
RX   PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA   Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA   Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT   "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT   sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC   -!- FUNCTION: Component of the 90S pre-ribosome involved in the maturation
CC       of rRNAs. Required for early cleavages of the pre-RNAs in the 40S
CC       ribosomal subunit maturation pathway (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with 90S and pre-40S pre-ribosomal particles.
CC       Interacts with CKA1, CKA2, CKB1, CKB2, PWP2, UTP15, UTP17 and UTP22 (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRP36 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FN394216; CAY86566.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8ZH37; -.
DR   SMR; C8ZH37; -.
DR   PRIDE; C8ZH37; -.
DR   EnsemblFungi; CAY86566; CAY86566; EC1118_1O4_5193g.
DR   HOGENOM; CLU_048802_3_0_1; -.
DR   Proteomes; UP000000286; Chromosome XV, Scaffold EC1118_1O4.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000469; P:cleavage involved in rRNA processing; IEA:InterPro.
DR   InterPro; IPR009292; RRP36.
DR   PANTHER; PTHR21738; PTHR21738; 1.
DR   Pfam; PF06102; RRP36; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Phosphoprotein; Ribonucleoprotein;
KW   Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..300
FT                   /note="rRNA biogenesis protein RRP36"
FT                   /id="PRO_0000397657"
FT   REGION          60..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          203..232
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        60..83
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        84..105
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        106..139
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         14
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q12481"
FT   MOD_RES         41
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q12481"
FT   MOD_RES         42
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q12481"
SQ   SEQUENCE   300 AA;  36099 MW;  A1ED18D4FA2C0D14 CRC64;
     MSYYFKNLKP DLNSDVEEDD GNLLESIMAN KSKREIDEQE SSDDELKTLS FGSLKKAETI
     IDEEDFKDTK PVHKKPITTT YREESFDEDD DSEDKSDEDA GFFEEDSEDE THHGQKVPKK
     KSKHAPIEQS SKKRVPRVRN IPGLEIPRNK RSNLYQDIRF DKSTGKALDS SIIRKRYQFL
     DEYREKEIDE LQKLLQDRKF LSKIDQGERE EMEQRLKSMK SRLQSMKNKD LEREILKEYE
     SDMNKNNNTR YHLKKSEKRK VVQKWKFDHM KAKQREKVME RKRKKRLGKE FKQFEFHNRR