ID   RRP41_NITMS             Reviewed;         244 AA.
AC   A9A5C9;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Exosome complex component Rrp41 {ECO:0000255|HAMAP-Rule:MF_00591};
DE            EC=3.1.13.- {ECO:0000255|HAMAP-Rule:MF_00591};
GN   Name=rrp41 {ECO:0000255|HAMAP-Rule:MF_00591}; OrderedLocusNames=Nmar_0432;
OS   Nitrosopumilus maritimus (strain SCM1).
OC   Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae;
OC   Nitrosopumilus.
OX   NCBI_TaxID=436308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCM1;
RX   PubMed=20421470; DOI=10.1073/pnas.0913533107;
RA   Walker C.B., de la Torre J.R., Klotz M.G., Urakawa H., Pinel N., Arp D.J.,
RA   Brochier-Armanet C., Chain P.S., Chan P.P., Gollabgir A., Hemp J.,
RA   Hugler M., Karr E.A., Konneke M., Shin M., Lawton T.J., Lowe T.,
RA   Martens-Habbena W., Sayavedra-Soto L.A., Lang D., Sievert S.M.,
RA   Rosenzweig A.C., Manning G., Stahl D.A.;
RT   "Nitrosopumilus maritimus genome reveals unique mechanisms for
RT   nitrification and autotrophy in globally distributed marine crenarchaea.";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:8818-8823(2010).
CC   -!- FUNCTION: Catalytic component of the exosome, which is a complex
CC       involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can
CC       also synthesize heteromeric RNA-tails. {ECO:0000255|HAMAP-
CC       Rule:MF_00591}.
CC   -!- SUBUNIT: Component of the archaeal exosome complex. Forms a hexameric
CC       ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The
CC       hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00591}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00591}.
CC   -!- SIMILARITY: Belongs to the RNase PH family. Rrp41 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00591}.
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DR   EMBL; CP000866; ABX12328.1; -; Genomic_DNA.
DR   AlphaFoldDB; A9A5C9; -.
DR   SMR; A9A5C9; -.
DR   STRING; 436308.Nmar_0432; -.
DR   EnsemblBacteria; ABX12328; ABX12328; Nmar_0432.
DR   KEGG; nmr:Nmar_0432; -.
DR   eggNOG; arCOG01575; Archaea.
DR   HOGENOM; CLU_063514_0_0_2; -.
DR   OMA; KGKGQGW; -.
DR   PhylomeDB; A9A5C9; -.
DR   Proteomes; UP000000792; Chromosome.
DR   GO; GO:0000177; C:cytoplasmic exosome (RNase complex); IBA:GO_Central.
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016075; P:rRNA catabolic process; IBA:GO_Central.
DR   CDD; cd11366; RNase_PH_archRRP41; 1.
DR   Gene3D; 3.30.230.70; -; 1.
DR   HAMAP; MF_00591; Exosome_Rrp41; 1.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR015847; ExoRNase_PH_dom2.
DR   InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR   InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR011807; Rrp41.
DR   Pfam; PF01138; RNase_PH; 1.
DR   Pfam; PF03725; RNase_PH_C; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55666; SSF55666; 1.
DR   TIGRFAMs; TIGR02065; ECX1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Exonuclease; Exosome; Hydrolase; Nuclease; Reference proteome.
FT   CHAIN           1..244
FT                   /note="Exosome complex component Rrp41"
FT                   /id="PRO_1000212171"
SQ   SEQUENCE   244 AA;  26612 MW;  F291FA399C8BB0E2 CRC64;
     MGGREATMVL MDENGKRCDG RTVDEPRRIM IKAGGLKNAD GSSYIEFGDN KILVGVFGPR
     DVHPKHMSDT DTGILRVRYH MEPFSVGERK NPAPSRREIE ISKVIKEALE PAVMLEKFPR
     TAVDVFIEVL QADGGTRCAA LTAASVALAD AGIPMRDMVA AIAAGKVADT VILDVNNEED
     QAGQADMPIG YMPNLEKITL LQLDGVLTPE EYKKCIQVGV DGCKLVYELQ KKALNDKYFG
     NKGD