RRP41_SULTO
ID RRP41_SULTO Reviewed; 243 AA.
AC Q975G8; F9VMZ0;
DT 25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT 14-DEC-2011, sequence version 2.
DT 25-MAY-2022, entry version 92.
DE RecName: Full=Exosome complex component Rrp41 {ECO:0000255|HAMAP-Rule:MF_00591};
DE EC=3.1.13.- {ECO:0000255|HAMAP-Rule:MF_00591};
GN Name=rrp41 {ECO:0000255|HAMAP-Rule:MF_00591}; OrderedLocusNames=STK_04430;
OS Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
OS (Sulfolobus tokodaii).
OC Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfurisphaera.
OX NCBI_TaxID=273063;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16993 / JCM 10545 / NBRC 100140 / 7;
RX PubMed=11572479; DOI=10.1093/dnares/8.4.123;
RA Kawarabayasi Y., Hino Y., Horikawa H., Jin-no K., Takahashi M., Sekine M.,
RA Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y.,
RA Nishijima K., Otsuka R., Nakazawa H., Takamiya M., Kato Y., Yoshizawa T.,
RA Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K.,
RA Masuda S., Yanagii M., Nishimura M., Yamagishi A., Oshima T., Kikuchi H.;
RT "Complete genome sequence of an aerobic thermoacidophilic Crenarchaeon,
RT Sulfolobus tokodaii strain7.";
RL DNA Res. 8:123-140(2001).
CC -!- FUNCTION: Catalytic component of the exosome, which is a complex
CC involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can
CC also synthesize heteromeric RNA-tails. {ECO:0000255|HAMAP-
CC Rule:MF_00591}.
CC -!- SUBUNIT: Component of the archaeal exosome complex. Forms a hexameric
CC ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The
CC hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
CC {ECO:0000255|HAMAP-Rule:MF_00591}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00591}.
CC -!- SIMILARITY: Belongs to the RNase PH family. Rrp41 subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_00591}.
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DR EMBL; BA000023; BAK54287.1; -; Genomic_DNA.
DR RefSeq; WP_052846320.1; NC_003106.2.
DR AlphaFoldDB; Q975G8; -.
DR SMR; Q975G8; -.
DR STRING; 273063.STK_04430; -.
DR EnsemblBacteria; BAK54287; BAK54287; STK_04430.
DR GeneID; 1458380; -.
DR KEGG; sto:STK_04430; -.
DR PATRIC; fig|273063.9.peg.515; -.
DR eggNOG; arCOG01575; Archaea.
DR OMA; KGKGQGW; -.
DR OrthoDB; 57069at2157; -.
DR Proteomes; UP000001015; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR GO; GO:0000175; F:3'-5'-exoribonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd11366; RNase_PH_archRRP41; 1.
DR Gene3D; 3.30.230.70; -; 1.
DR HAMAP; MF_00591; Exosome_Rrp41; 1.
DR InterPro; IPR001247; ExoRNase_PH_dom1.
DR InterPro; IPR015847; ExoRNase_PH_dom2.
DR InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR InterPro; IPR011807; Rrp41.
DR Pfam; PF01138; RNase_PH; 1.
DR Pfam; PF03725; RNase_PH_C; 1.
DR SUPFAM; SSF54211; SSF54211; 1.
DR SUPFAM; SSF55666; SSF55666; 1.
DR TIGRFAMs; TIGR02065; ECX1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Exonuclease; Exosome; Hydrolase; Nuclease; Reference proteome.
FT CHAIN 1..243
FT /note="Exosome complex component Rrp41"
FT /id="PRO_0000139992"
SQ SEQUENCE 243 AA; 27101 MW; 59760959D44C8832 CRC64;
MIQLQKPRLI LDNGLRLDGR KPDEMRPIKI ELGVLKNADG SAIFEMGNTK VIAAVYGPKE
MHPRHLALPD RAVLRVRYHM TPFSTDERKN PAPSRREIEL SKVIREALES TILVELFPRT
VIDVFMEVLQ ADAGTRLVSL MAASMALADA GIPMRDLIAG VAVGKADGVL VLDLNEPEDM
WGEADMPVAM MPSLKQVALL QLNGNMTPQE FRQALEMAQK GIETIYNLEK EAIRSKYAEL
KEE
