ID   RRP42_AERPE             Reviewed;         276 AA.
AC   Q9YC05;
DT   25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Exosome complex component Rrp42 {ECO:0000255|HAMAP-Rule:MF_00622};
GN   Name=rrp42 {ECO:0000255|HAMAP-Rule:MF_00622}; OrderedLocusNames=APE_1445;
OS   Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 /
OS   K1).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Aeropyrum.
OX   NCBI_TaxID=272557;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1;
RX   PubMed=10382966; DOI=10.1093/dnares/6.2.83;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K.,
RA   Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A.,
RA   Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
RT   "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon,
RT   Aeropyrum pernix K1.";
RL   DNA Res. 6:83-101(1999).
CC   -!- FUNCTION: Non-catalytic component of the exosome, which is a complex
CC       involved in RNA degradation. Contributes to the structuring of the
CC       Rrp41 active site. {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SUBUNIT: Component of the archaeal exosome complex. Forms a hexameric
CC       ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The
CC       hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SIMILARITY: Belongs to the RNase PH family. Rrp42 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00622}.
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DR   EMBL; BA000002; BAA80443.1; -; Genomic_DNA.
DR   PIR; E72623; E72623.
DR   AlphaFoldDB; Q9YC05; -.
DR   SMR; Q9YC05; -.
DR   STRING; 272557.APE_1445; -.
DR   EnsemblBacteria; BAA80443; BAA80443; APE_1445.
DR   KEGG; ape:APE_1445; -.
DR   PATRIC; fig|272557.25.peg.977; -.
DR   eggNOG; arCOG01574; Archaea.
DR   OMA; PESVFEM; -.
DR   Proteomes; UP000002518; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd11365; RNase_PH_archRRP42; 1.
DR   Gene3D; 3.30.230.70; -; 1.
DR   HAMAP; MF_00622; Exosome_Rrp42; 1.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR015847; ExoRNase_PH_dom2.
DR   InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR   InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR020869; Rrp42_archaea.
DR   Pfam; PF01138; RNase_PH; 1.
DR   Pfam; PF03725; RNase_PH_C; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55666; SSF55666; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Exosome; Reference proteome.
FT   CHAIN           1..276
FT                   /note="Exosome complex component Rrp42"
FT                   /id="PRO_0000139995"
SQ   SEQUENCE   276 AA;  30162 MW;  303755CB110CBDD0 CRC64;
     MSITPHRLPV APVIVREAYL SLLRKGWRPG DRDLKTPRNV KIETGIIEKA EGSALVKLGK
     TQVIAGVKAG VGAPFKDTPN QGVLTVHAEF VPLASPVFEP GPPDENAIEL ARVVDRSLRE
     VGAVDLESLV IRPGEKVWVL WVDLYIIDHD GNLFDASMLA TMAVLLTARL PRYEESETGE
     IIISKEGEGE ELKVKTRVVT VTTAKIDRYI VVDPNIEEEA VSDVRLVTAV DENGRIVGLQ
     KTGMGSLTEA DIETMIGYSL EASKVYFKAL EEAIKP