RRP42_METAR
ID RRP42_METAR Reviewed; 260 AA.
AC Q0W2Y7;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Exosome complex component Rrp42 {ECO:0000255|HAMAP-Rule:MF_00622};
GN Name=rrp42 {ECO:0000255|HAMAP-Rule:MF_00622};
GN OrderedLocusNames=UNCMA_09920; ORFNames=RCIX2125;
OS Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanocellales; Methanocellaceae; Methanocella.
OX NCBI_TaxID=351160;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22066 / NBRC 105507 / MRE50;
RX PubMed=16857943; DOI=10.1126/science.1127062;
RA Erkel C., Kube M., Reinhardt R., Liesack W.;
RT "Genome of rice cluster I archaea -- the key methane producers in the rice
RT rhizosphere.";
RL Science 313:370-372(2006).
CC -!- FUNCTION: Non-catalytic component of the exosome, which is a complex
CC involved in RNA degradation. Contributes to the structuring of the
CC Rrp41 active site. {ECO:0000255|HAMAP-Rule:MF_00622}.
CC -!- SUBUNIT: Component of the archaeal exosome complex. Forms a hexameric
CC ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The
CC hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
CC {ECO:0000255|HAMAP-Rule:MF_00622}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00622}.
CC -!- SIMILARITY: Belongs to the RNase PH family. Rrp42 subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_00622}.
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DR EMBL; AM114193; CAJ37256.1; -; Genomic_DNA.
DR RefSeq; WP_012035320.1; NC_009464.1.
DR AlphaFoldDB; Q0W2Y7; -.
DR SMR; Q0W2Y7; -.
DR STRING; 351160.RCIX2125; -.
DR EnsemblBacteria; CAJ37256; CAJ37256; RCIX2125.
DR GeneID; 5144518; -.
DR KEGG; rci:RCIX2125; -.
DR PATRIC; fig|351160.9.peg.1025; -.
DR eggNOG; arCOG01574; Archaea.
DR OMA; PESVFEM; -.
DR OrthoDB; 64101at2157; -.
DR Proteomes; UP000000663; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd11365; RNase_PH_archRRP42; 1.
DR Gene3D; 3.30.230.70; -; 1.
DR HAMAP; MF_00622; Exosome_Rrp42; 1.
DR InterPro; IPR001247; ExoRNase_PH_dom1.
DR InterPro; IPR015847; ExoRNase_PH_dom2.
DR InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR InterPro; IPR020869; Rrp42_archaea.
DR Pfam; PF01138; RNase_PH; 1.
DR Pfam; PF03725; RNase_PH_C; 1.
DR SUPFAM; SSF54211; SSF54211; 1.
DR SUPFAM; SSF55666; SSF55666; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Exosome; Reference proteome.
FT CHAIN 1..260
FT /note="Exosome complex component Rrp42"
FT /id="PRO_1000051553"
SQ SEQUENCE 260 AA; 27732 MW; 8496E7345A0FB42B CRC64;
MSEDVIAEIK RDYIYSLANQ GDRADGRKFD EFRAISVETG VINKAEGSAR VKIGDSQVVV
GVKIQPGEPF PDTPDSGVII TNLELVPLAS PTFESGPPRE DAIELARVVD RGVRESGAID
LSKLCIESGQ KVWMVFIDVH VLDHDGNLMD AASLGAIAAL KATKIPNSKF GLGEDVKLPL
NDVPIGVTAV NIGGAIMLDP SLDEESVAPC KLTVITNKEG AISGMQKSGV GTLTPDQINH
IIRLAKEKAN VLREKLEGIQ