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RRP42_PYRAE
ID   RRP42_PYRAE             Reviewed;         274 AA.
AC   Q8ZVN0;
DT   25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Exosome complex component Rrp42 {ECO:0000255|HAMAP-Rule:MF_00622};
GN   Name=rrp42 {ECO:0000255|HAMAP-Rule:MF_00622}; OrderedLocusNames=PAE2206;
OS   Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP
OS   104966 / NBRC 100827 / IM2).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Pyrobaculum.
OX   NCBI_TaxID=178306;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2;
RX   PubMed=11792869; DOI=10.1073/pnas.241636498;
RA   Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I.,
RA   Miller J.H.;
RT   "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum
RT   aerophilum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002).
CC   -!- FUNCTION: Non-catalytic component of the exosome, which is a complex
CC       involved in RNA degradation. Contributes to the structuring of the
CC       Rrp41 active site. {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SUBUNIT: Component of the archaeal exosome complex. Forms a hexameric
CC       ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The
CC       hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SIMILARITY: Belongs to the RNase PH family. Rrp42 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00622}.
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DR   EMBL; AE009441; AAL64026.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8ZVN0; -.
DR   SMR; Q8ZVN0; -.
DR   STRING; 178306.PAE2206; -.
DR   EnsemblBacteria; AAL64026; AAL64026; PAE2206.
DR   KEGG; pai:PAE2206; -.
DR   PATRIC; fig|178306.9.peg.1638; -.
DR   eggNOG; arCOG01574; Archaea.
DR   HOGENOM; CLU_038194_0_0_2; -.
DR   InParanoid; Q8ZVN0; -.
DR   OMA; PESVFEM; -.
DR   Proteomes; UP000002439; Chromosome.
DR   GO; GO:0000177; C:cytoplasmic exosome (RNase complex); IBA:GO_Central.
DR   GO; GO:0016075; P:rRNA catabolic process; IBA:GO_Central.
DR   CDD; cd11365; RNase_PH_archRRP42; 1.
DR   Gene3D; 3.30.230.70; -; 1.
DR   HAMAP; MF_00622; Exosome_Rrp42; 1.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR015847; ExoRNase_PH_dom2.
DR   InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR   InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR020869; Rrp42_archaea.
DR   Pfam; PF01138; RNase_PH; 1.
DR   Pfam; PF03725; RNase_PH_C; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55666; SSF55666; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Exosome; Reference proteome.
FT   CHAIN           1..274
FT                   /note="Exosome complex component Rrp42"
FT                   /id="PRO_0000140002"
SQ   SEQUENCE   274 AA;  29775 MW;  22C87D07140ADA48 CRC64;
     MASISPYGKR FISYLRREQI RRLLATKYRV DGRGPEQTRN VEINVGVVKT ADGSAEVKLG
     KTHVVAGVKV GLGQPFPDAP DEGVLVVNAE VLPHASPYTE VGPPDEFAIE LARVVDRGIR
     HCGYVDFKKL AVEGGKAYVL WIDLYVINDD GNLIDVANLA SVAALKNTQL PVVVKDEAGV
     VKLDRNNKAP LPVDISKAPI AVSVGKIGNV LFLDPTFEEE LSLDGRITFT FSEDKIVAAQ
     KTLGYFTQSE IEAALNLALR GRDRLLEALK SALK
 
 
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