ID   RRP42_SULIK             Reviewed;         275 AA.
AC   C4KHE3;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Exosome complex component Rrp42 {ECO:0000255|HAMAP-Rule:MF_00622};
GN   Name=rrp42 {ECO:0000255|HAMAP-Rule:MF_00622}; OrderedLocusNames=M164_1401;
OS   Sulfolobus islandicus (strain M.16.4 / Kamchatka #3).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=426118;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M.16.4 / Kamchatka #3;
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC   -!- FUNCTION: Non-catalytic component of the exosome, which is a complex
CC       involved in RNA degradation. Contributes to the structuring of the
CC       Rrp41 active site. {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SUBUNIT: Component of the archaeal exosome complex. Forms a hexameric
CC       ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The
CC       hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SIMILARITY: Belongs to the RNase PH family. Rrp42 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00622}.
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DR   EMBL; CP001402; ACR42007.1; -; Genomic_DNA.
DR   RefSeq; WP_012713728.1; NC_012726.1.
DR   AlphaFoldDB; C4KHE3; -.
DR   SMR; C4KHE3; -.
DR   EnsemblBacteria; ACR42007; ACR42007; M164_1401.
DR   GeneID; 7806795; -.
DR   GeneID; 7939920; -.
DR   GeneID; 8761440; -.
DR   KEGG; sid:M164_1401; -.
DR   HOGENOM; CLU_038194_0_0_2; -.
DR   OMA; PESVFEM; -.
DR   Proteomes; UP000001479; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd11365; RNase_PH_archRRP42; 1.
DR   Gene3D; 3.30.230.70; -; 1.
DR   HAMAP; MF_00622; Exosome_Rrp42; 1.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR015847; ExoRNase_PH_dom2.
DR   InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR   InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR020869; Rrp42_archaea.
DR   Pfam; PF01138; RNase_PH; 1.
DR   Pfam; PF03725; RNase_PH_C; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55666; SSF55666; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Exosome.
FT   CHAIN           1..275
FT                   /note="Exosome complex component Rrp42"
FT                   /id="PRO_1000212290"
SQ   SEQUENCE   275 AA;  30282 MW;  A82916406416F918 CRC64;
     MSSTPSNQNI IPLIKKESIV SLFEKGTRQD GRKLTDYRPL SITLDYAKKA DGSALVKLGT
     TMVLAGTKLE IDKPYEDTPN QGNLIVNVEL LPLAYETFEP GPPDENAIEL ARVVDRSLRD
     SKALDLTKLV IEPGKSVWTV WLDVYVLDYG GNVLDACTLA SVAALYNTKV YKVEQDSNGF
     RVNKNEVVGK LPLNHPVVTV SIAKVDKYLI VDPDLDEESI MDTKVSFSYT PDLKIVGIQK
     SGKGSMSLQD IDQAENTARL VAVKLLEELK KQLGI