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RRP42_THEAC
ID   RRP42_THEAC             Reviewed;         260 AA.
AC   Q9HIP1;
DT   25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   25-MAR-2003, sequence version 2.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Exosome complex component Rrp42 {ECO:0000255|HAMAP-Rule:MF_00622};
GN   Name=rrp42 {ECO:0000255|HAMAP-Rule:MF_00622}; OrderedLocusNames=Ta1294;
OS   Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC
OS   15155 / AMRC-C165).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Thermoplasmataceae; Thermoplasma.
OX   NCBI_TaxID=273075;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165;
RX   PubMed=11029001; DOI=10.1038/35035069;
RA   Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C.,
RA   Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.;
RT   "The genome sequence of the thermoacidophilic scavenger Thermoplasma
RT   acidophilum.";
RL   Nature 407:508-513(2000).
CC   -!- FUNCTION: Non-catalytic component of the exosome, which is a complex
CC       involved in RNA degradation. Contributes to the structuring of the
CC       Rrp41 active site. {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SUBUNIT: Component of the archaeal exosome complex. Forms a hexameric
CC       ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The
CC       hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SIMILARITY: Belongs to the RNase PH family. Rrp42 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAC12416.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AL445067; CAC12416.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_010901699.1; NC_002578.1.
DR   AlphaFoldDB; Q9HIP1; -.
DR   SMR; Q9HIP1; -.
DR   STRING; 273075.Ta1294m; -.
DR   EnsemblBacteria; CAC12416; CAC12416; CAC12416.
DR   GeneID; 1457094; -.
DR   KEGG; tac:Ta1294; -.
DR   eggNOG; arCOG01574; Archaea.
DR   HOGENOM; CLU_038194_0_0_2; -.
DR   OMA; PESVFEM; -.
DR   OrthoDB; 64101at2157; -.
DR   Proteomes; UP000001024; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd11365; RNase_PH_archRRP42; 1.
DR   Gene3D; 3.30.230.70; -; 1.
DR   HAMAP; MF_00622; Exosome_Rrp42; 1.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR015847; ExoRNase_PH_dom2.
DR   InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR   InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR020869; Rrp42_archaea.
DR   Pfam; PF01138; RNase_PH; 1.
DR   Pfam; PF03725; RNase_PH_C; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55666; SSF55666; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Exosome; Reference proteome.
FT   CHAIN           1..260
FT                   /note="Exosome complex component Rrp42"
FT                   /id="PRO_0000140008"
SQ   SEQUENCE   260 AA;  28362 MW;  B55CEF7A17F0F6EC CRC64;
     MVKESAEILS EIRKNYILST MKGGKRIDGR LPDEFRELTI IENYIPRANG SAYVALGNTR
     VVAGVKIEAG EPFPDTPDQG VLTTNVELLP IAFPSFEAGP PNDLAIEVSR VVDRGIRESK
     MISPEKLVIE QGKKVWIVFL DINVLDYDGN LIDASTIAAV AALRNAVVPA SKEGGEDFKL
     PVSSTPISVT MVKIGDTLVC DPSLEEDQIC GGRITVTTTE DGHIRAMQKG EIGAFTVEDV
     KKAVKMSLEV GKKLREKYFR
 
 
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