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RRP42_THEGJ
ID   RRP42_THEGJ             Reviewed;         273 AA.
AC   C5A2B8;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Exosome complex component Rrp42 {ECO:0000255|HAMAP-Rule:MF_00622};
GN   Name=rrp42 {ECO:0000255|HAMAP-Rule:MF_00622}; OrderedLocusNames=TGAM_2035;
OS   Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=593117;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15229 / JCM 11827 / EJ3;
RX   PubMed=19558674; DOI=10.1186/gb-2009-10-6-r70;
RA   Zivanovic Y., Armengaud J., Lagorce A., Leplat C., Guerin P., Dutertre M.,
RA   Anthouard V., Forterre P., Wincker P., Confalonieri F.;
RT   "Genome analysis and genome-wide proteomics of Thermococcus gammatolerans,
RT   the most radioresistant organism known amongst the Archaea.";
RL   Genome Biol. 10:R70.1-R70.23(2007).
CC   -!- FUNCTION: Non-catalytic component of the exosome, which is a complex
CC       involved in RNA degradation. Contributes to the structuring of the
CC       Rrp41 active site. {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SUBUNIT: Component of the archaeal exosome complex. Forms a hexameric
CC       ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The
CC       hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00622}.
CC   -!- SIMILARITY: Belongs to the RNase PH family. Rrp42 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00622}.
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DR   EMBL; CP001398; ACS34537.1; -; Genomic_DNA.
DR   RefSeq; WP_015859640.1; NC_012804.1.
DR   AlphaFoldDB; C5A2B8; -.
DR   SMR; C5A2B8; -.
DR   STRING; 593117.TGAM_2035; -.
DR   PaxDb; C5A2B8; -.
DR   EnsemblBacteria; ACS34537; ACS34537; TGAM_2035.
DR   GeneID; 7988601; -.
DR   KEGG; tga:TGAM_2035; -.
DR   PATRIC; fig|593117.10.peg.2046; -.
DR   eggNOG; arCOG01574; Archaea.
DR   HOGENOM; CLU_038194_0_0_2; -.
DR   OMA; PESVFEM; -.
DR   OrthoDB; 64101at2157; -.
DR   Proteomes; UP000001488; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd11365; RNase_PH_archRRP42; 1.
DR   Gene3D; 3.30.230.70; -; 1.
DR   HAMAP; MF_00622; Exosome_Rrp42; 1.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR015847; ExoRNase_PH_dom2.
DR   InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR   InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR020869; Rrp42_archaea.
DR   Pfam; PF01138; RNase_PH; 1.
DR   Pfam; PF03725; RNase_PH_C; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55666; SSF55666; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Exosome.
FT   CHAIN           1..273
FT                   /note="Exosome complex component Rrp42"
FT                   /id="PRO_1000212295"
SQ   SEQUENCE   273 AA;  29974 MW;  86C735ED8867EB5D CRC64;
     MSDVEIMAGI MRDRILNLLK EGKRIDGRSF EEYRDIEIKT GFIEKAEGSA WVRLGGTRVL
     VGIKVDVGEP FPDLPDRGVM TTNVELVPLA SPTFEPGPPD ERAIELARVI DRGIRESQAV
     ELEKLVIVPG KLVRVVFIDV HVLDHDGNLF DATGLAAMAA LMTTKIPKVE YNEETGEIIK
     LDEYEPLPVK HVPIPVTFAK IGSSIIVDPN LDEETVMDSR LTITTDETGH ISAVQKGEGG
     SFKLEEVMYA IDTALKKADE LRKILLEAVG SAS
 
 
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