RRS1_ARATH
ID RRS1_ARATH Reviewed; 318 AA.
AC Q9SH88; Q56WN3; Q8LA50;
DT 06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 2.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Ribosome biogenesis regulatory protein homolog;
GN OrderedLocusNames=At2g37990; ORFNames=T8P21.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 111-318.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in ribosome biogenesis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRS1 family. {ECO:0000305}.
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DR EMBL; CP002685; AEC09475.1; -; Genomic_DNA.
DR EMBL; AY088030; AAM65576.1; -; mRNA.
DR EMBL; AK222003; BAD94617.1; -; mRNA.
DR PIR; F84799; F84799.
DR RefSeq; NP_565878.1; NM_129356.3.
DR AlphaFoldDB; Q9SH88; -.
DR SMR; Q9SH88; -.
DR BioGRID; 3721; 3.
DR STRING; 3702.AT2G37990.1; -.
DR PaxDb; Q9SH88; -.
DR PRIDE; Q9SH88; -.
DR ProteomicsDB; 236198; -.
DR EnsemblPlants; AT2G37990.1; AT2G37990.1; AT2G37990.
DR GeneID; 818377; -.
DR Gramene; AT2G37990.1; AT2G37990.1; AT2G37990.
DR KEGG; ath:AT2G37990; -.
DR Araport; AT2G37990; -.
DR TAIR; locus:2065553; AT2G37990.
DR eggNOG; KOG1765; Eukaryota.
DR HOGENOM; CLU_065163_0_0_1; -.
DR InParanoid; Q9SH88; -.
DR OMA; LLINEIW; -.
DR OrthoDB; 1264304at2759; -.
DR PhylomeDB; Q9SH88; -.
DR PRO; PR:Q9SH88; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SH88; baseline and differential.
DR Genevisible; Q9SH88; AT.
DR GO; GO:0005730; C:nucleolus; HDA:TAIR.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IBA:GO_Central.
DR InterPro; IPR007023; Ribosom_reg.
DR PANTHER; PTHR17602; PTHR17602; 1.
DR Pfam; PF04939; RRS1; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..318
FT /note="Ribosome biogenesis regulatory protein homolog"
FT /id="PRO_0000185377"
FT REGION 59..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 139..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 217..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 289..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 28
FT /note="P -> S (in Ref. 3; AAM65576)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 318 AA; 35531 MW; 55FF1F4159078CE3 CRC64;
MDTEMETEQI YQVDVGNLLA FNPNHRFPSA PSSRGELVKE ILTEGTKLVQ EIANKLFNFP
STETNDGPIV QLPPPTTKLP REKHIPRPKP PTKWEEFALK KGIQKRKKEK VVWDEQTNQF
KRRHGYDRVN DDNDVPIIEA KESDEPGVDP FAKRLDDKKK RVGKQEKNRL QNLKAAEKAG
ALPSHVQLAA TSLPISGTKA QPKKIGKDEL GDVAGLAATS TASGGKFDKK LPGEKPPKKQ
GKHHKYLPVV SGRGDVNAEK EQTNNVLSKI FSKHSHEILN VGKAINMYNV KKEKKKSGRS
DKLKPKKDIT KKPANKAK
