RRS1_CAEBR
ID RRS1_CAEBR Reviewed; 329 AA.
AC A8WY26;
DT 15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 1.
DT 03-AUG-2022, entry version 66.
DE RecName: Full=Ribosome biogenesis regulatory protein homolog {ECO:0000250|UniProtKB:Q9XVT0};
GN Name=rrbs-1 {ECO:0000312|EMBL:CAP25286.1}; ORFNames=CBG04617;
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16;
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R.M., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- FUNCTION: Involved in ribosomal large subunit assembly.
CC {ECO:0000250|UniProtKB:Q15050}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q15050}.
CC -!- SIMILARITY: Belongs to the RRS1 family. {ECO:0000255}.
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DR EMBL; HE601135; CAP25286.1; -; Genomic_DNA.
DR RefSeq; XP_002637827.1; XM_002637781.1.
DR AlphaFoldDB; A8WY26; -.
DR SMR; A8WY26; -.
DR STRING; 6238.CBG04617; -.
DR PRIDE; A8WY26; -.
DR EnsemblMetazoa; CBG04617.1; CBG04617.1; WBGene00027255.
DR GeneID; 8579824; -.
DR KEGG; cbr:CBG_04617; -.
DR CTD; 8579824; -.
DR WormBase; CBG04617; CBP21483; WBGene00027255; Cbr-rrbs-1.
DR eggNOG; KOG1765; Eukaryota.
DR HOGENOM; CLU_065163_1_0_1; -.
DR InParanoid; A8WY26; -.
DR OMA; LLINEIW; -.
DR OrthoDB; 1264304at2759; -.
DR Proteomes; UP000008549; Chromosome V.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000027; P:ribosomal large subunit assembly; ISS:UniProtKB.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IBA:GO_Central.
DR InterPro; IPR007023; Ribosom_reg.
DR PANTHER; PTHR17602; PTHR17602; 1.
DR Pfam; PF04939; RRS1; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..329
FT /note="Ribosome biogenesis regulatory protein homolog"
FT /id="PRO_0000394764"
FT REGION 227..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..246
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..318
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 37835 MW; BEB99AFDF1A433A0 CRC64;
MADKSTEVEK AIDPIIDLGN LLFIDREPLQ GDAEEGLEER ARKNTQLLFN NIWQLEQKRV
EEAIIVTLPA ATYRLPREKK LPEKKEPTKW EKYAKEKGIE KRKKDKKVFD EATKEWKPTY
GYRRGNDNTK DWLIEIPDNA EDPNKDFFAE RREKKKERVA KNEMQRMKNL ARQMKTTVKT
GPSTDKMIGV GIDAKDKSKQ DVRFAVDRAK LATASAGKFQ EGLKGEKANI KTGKKRKFES
NEAPVSAEKE RALQILQRMK SKKAKIVEEK ASAVAGPLRE KKEKQEKKGA KEATRQKSQI
HRQQWFKNKV DSKKKGTGGA KKKGANKRK
