RRS1_CAEEL
ID RRS1_CAEEL Reviewed; 333 AA.
AC Q9XVT0;
DT 06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Ribosome biogenesis regulatory protein homolog;
GN Name=rrbs-1; ORFNames=C15H11.9;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Involved in ribosomal large subunit assembly.
CC {ECO:0000250|UniProtKB:Q15050}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q15050}.
CC -!- SIMILARITY: Belongs to the RRS1 family. {ECO:0000305}.
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DR EMBL; Z81035; CAB02731.1; -; Genomic_DNA.
DR PIR; T19313; T19313.
DR RefSeq; NP_506573.1; NM_074172.4.
DR AlphaFoldDB; Q9XVT0; -.
DR SMR; Q9XVT0; -.
DR BioGRID; 44946; 11.
DR DIP; DIP-24987N; -.
DR STRING; 6239.C15H11.9; -.
DR EPD; Q9XVT0; -.
DR PaxDb; Q9XVT0; -.
DR PeptideAtlas; Q9XVT0; -.
DR EnsemblMetazoa; C15H11.9.1; C15H11.9.1; WBGene00007617.
DR GeneID; 179942; -.
DR KEGG; cel:CELE_C15H11.9; -.
DR UCSC; C15H11.9.1; c. elegans.
DR CTD; 179942; -.
DR WormBase; C15H11.9; CE08186; WBGene00007617; rrbs-1.
DR eggNOG; KOG1765; Eukaryota.
DR GeneTree; ENSGT00390000005213; -.
DR HOGENOM; CLU_065163_1_0_1; -.
DR InParanoid; Q9XVT0; -.
DR OMA; LLINEIW; -.
DR OrthoDB; 1264304at2759; -.
DR PhylomeDB; Q9XVT0; -.
DR PRO; PR:Q9XVT0; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00007617; Expressed in larva and 4 other tissues.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000027; P:ribosomal large subunit assembly; ISS:UniProtKB.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IBA:GO_Central.
DR InterPro; IPR007023; Ribosom_reg.
DR PANTHER; PTHR17602; PTHR17602; 1.
DR Pfam; PF04939; RRS1; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..333
FT /note="Ribosome biogenesis regulatory protein homolog"
FT /id="PRO_0000185376"
FT REGION 227..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..246
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..318
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 333 AA; 37986 MW; 88E91737402FC4CE CRC64;
MADKSTEVEK AIDPIIDLGN LLFIDREPIQ GDASEGLEER ARKNTQLLFN NIWQLEQKRV
EEAIIVTLPP ATYRLPREKR LPEKKEPTKW EKYAAEKGIE KRKKDKKVFD EATKEWKPTY
GYRRGNDDTK DWLIEIPDNA EDPNKDFFAE RREKKKERVA KNDMQRMKNL ARQMKTTVKS
GPSTEKMIGV GVDAKEKSKQ QVRFAVDRAK LATASAGKFQ EGLKGEKANV KTGKKRKFEA
NEAPVSGEKE RALQILQRMK SKKAKIVEEK AAAVAGPLRE KKEKSERKGA KDQTRQKSQI
HRQQWFKNKV DGKKKGTGGA GKKGANKAKA RKG
