ID   RRT13_YEAST             Reviewed;         185 AA.
AC   P40042; D3DLX1;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 149.
DE   RecName: Full=Regulator of rDNA transcription protein 13;
GN   Name=RRT13; OrderedLocusNames=YER066W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169868;
RA   Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA   Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA   Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA   Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA   Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA   Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA   Botstein D., Davis R.W.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL   Nature 387:78-81(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   FUNCTION.
RX   PubMed=19270272; DOI=10.1534/genetics.108.100313;
RA   Hontz R.D., Niederer R.O., Johnson J.M., Smith J.S.;
RT   "Genetic identification of factors that modulate ribosomal DNA
RT   transcription in Saccharomyces cerevisiae.";
RL   Genetics 182:105-119(2009).
CC   -!- FUNCTION: May be involved in the modulation of rDNA transcription.
CC       {ECO:0000269|PubMed:19270272}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U18813; AAB64602.1; -; Genomic_DNA.
DR   EMBL; BK006939; DAA07725.1; -; Genomic_DNA.
DR   PIR; S50569; S50569.
DR   RefSeq; NP_010988.1; NM_001178957.1.
DR   AlphaFoldDB; P40042; -.
DR   SMR; P40042; -.
DR   BioGRID; 36809; 45.
DR   DIP; DIP-2848N; -.
DR   IntAct; P40042; 2.
DR   MINT; P40042; -.
DR   STRING; 4932.YER066W; -.
DR   PaxDb; P40042; -.
DR   EnsemblFungi; YER066W_mRNA; YER066W; YER066W.
DR   GeneID; 856796; -.
DR   KEGG; sce:YER066W; -.
DR   SGD; S000000868; RRT13.
DR   VEuPathDB; FungiDB:YER066W; -.
DR   eggNOG; KOG0274; Eukaryota.
DR   GeneTree; ENSGT00940000174696; -.
DR   HOGENOM; CLU_1462435_0_0_1; -.
DR   InParanoid; P40042; -.
DR   OMA; IRTIDWI; -.
DR   BioCyc; YEAST:G3O-30240-MON; -.
DR   PRO; PR:P40042; -.
DR   Proteomes; UP000002311; Chromosome V.
DR   RNAct; P40042; protein.
DR   GO; GO:0019005; C:SCF ubiquitin ligase complex; IBA:GO_Central.
DR   GO; GO:1990756; F:ubiquitin ligase-substrate adaptor activity; IBA:GO_Central.
DR   GO; GO:0000209; P:protein polyubiquitination; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 3.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Reference proteome; Repeat; Transcription; Transcription regulation;
KW   WD repeat.
FT   CHAIN           1..185
FT                   /note="Regulator of rDNA transcription protein 13"
FT                   /id="PRO_0000051472"
FT   REPEAT          9..48
FT                   /note="WD 1"
FT   REPEAT          71..108
FT                   /note="WD 2"
FT   REPEAT          111..148
FT                   /note="WD 3"
SQ   SEQUENCE   185 AA;  20686 MW;  A07DCF8B3CA30399 CRC64;
     MKCLYILSGH TDRIYSTIYD HERKRCISAS MDTTIRIWDL ENIRNNGECS YATNSASPCA
     KILGAMYTLR GHRALVGLLG LSDKFLVSAS VDGSIRCWDA NTYFLKHFFD HTQLNTITAL
     HVSDEVLVSG SEGLLNIYDL NSGLLVRSDT LSGADNVWNV SFKDNTLVAA VERDKRNLLE
     ILDFS