RRT14_CANAL
ID RRT14_CANAL Reviewed; 219 AA.
AC Q5AJ85; A0A1D8PJ69;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2017, sequence version 2.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Regulator of rDNA transcription 14;
GN Name=RRT14; OrderedLocusNames=CAALFM_C301430WA;
GN ORFNames=CaO19.1708, CaO19.9275;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- FUNCTION: Involved in ribosome biogenesis, probably through modulation
CC of rDNA transcription. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRT14 family. {ECO:0000305}.
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DR EMBL; CP017625; AOW28185.1; -; Genomic_DNA.
DR RefSeq; XP_721779.2; XM_716686.2.
DR AlphaFoldDB; Q5AJ85; -.
DR SMR; Q5AJ85; -.
DR STRING; 237561.Q5AJ85; -.
DR GeneID; 3636633; -.
DR KEGG; cal:CAALFM_C301430WA; -.
DR CGD; CAL0000186307; orf19.9275.
DR VEuPathDB; FungiDB:C3_01430W_A; -.
DR eggNOG; ENOG502S1G1; Eukaryota.
DR HOGENOM; CLU_095038_0_0_1; -.
DR InParanoid; Q5AJ85; -.
DR OMA; IKYNHIK; -.
DR OrthoDB; 1637700at2759; -.
DR PRO; PR:Q5AJ85; -.
DR Proteomes; UP000000559; Chromosome 3.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR InterPro; IPR031404; Rrt14.
DR Pfam; PF17075; RRT14; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..219
FT /note="Regulator of rDNA transcription 14"
FT /id="PRO_0000404336"
FT REGION 27..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 219 AA; 24911 MW; 20102BE4075F79F4 CRC64;
MSFNSNASKY QAENTVDKLF SNILHTSTTS KSVSKSKSKS KSKPKPISST QLLVNQLQST
NTTANNNNTK RKKHNNNKRI NKTLLEEKKF SKFIKYNHIK QKSNKSELDE KYLNKLVRKN
INSLNKINKI DDLLIDEELN QIKQELLEEN EFVGMGGGQL KGGKRLRKKL LNNTKQVIDE
FDGFGEISSS NNNNKKKNSS YPGLTPGLAP VDYEEEDNE