RRT14_CANAW
ID RRT14_CANAW Reviewed; 219 AA.
AC C4YPS3;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 35.
DE RecName: Full=Regulator of rDNA transcription 14;
GN Name=RRT14; ORFNames=CAWG_02475;
OS Candida albicans (strain WO-1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294748;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WO-1;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Involved in ribosome biogenesis, probably through modulation
CC of rDNA transcription. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRT14 family. {ECO:0000305}.
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DR EMBL; CM000310; EEQ44212.1; -; Genomic_DNA.
DR AlphaFoldDB; C4YPS3; -.
DR SMR; C4YPS3; -.
DR STRING; 5476.C4YPS3; -.
DR EnsemblFungi; EEQ44212; EEQ44212; CAWG_02475.
DR VEuPathDB; FungiDB:CAWG_02475; -.
DR HOGENOM; CLU_095038_0_0_1; -.
DR OMA; IKYNHIK; -.
DR Proteomes; UP000001429; Chromosome 3.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR InterPro; IPR031404; Rrt14.
DR Pfam; PF17075; RRT14; 1.
PE 3: Inferred from homology;
KW Nucleus; Transcription; Transcription regulation.
FT CHAIN 1..219
FT /note="Regulator of rDNA transcription 14"
FT /id="PRO_0000404335"
FT REGION 27..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 60..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 184..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 219 AA; 24886 MW; 201ED788775F79F4 CRC64;
MSFNSNASKY QAENTVDKLF SNILHTSTTS KSVSKSKSKS KSKPKPISST QLLVNQLQST
NTTANNNNTK RKKHNNNKRI NKTLLEEKKF SKFIKYNHIK QKSNKSELDE KYLNKLVRKN
INSLNKINKI DDLLIDEELN QIKQELLEEN EFVGMGGGQL KGGKRLRKKL LNNTKQVIDE
FDGFGEISSS NNNNKKKNSS HPGLTPGLAP VDYEEEDDE