ID   RRT14_KLULA             Reviewed;         201 AA.
AC   Q6CLA4;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Regulator of rDNA transcription 14;
GN   Name=RRT14; OrderedLocusNames=KLLA0F04543g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in ribosome biogenesis, probably through modulation
CC       of rDNA transcription. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRT14 family. {ECO:0000305}.
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DR   EMBL; CR382126; CAG97993.1; -; Genomic_DNA.
DR   RefSeq; XP_455285.1; XM_455285.1.
DR   AlphaFoldDB; Q6CLA4; -.
DR   SMR; Q6CLA4; -.
DR   STRING; 28985.XP_455285.1; -.
DR   EnsemblFungi; CAG97993; CAG97993; KLLA0_F04543g.
DR   GeneID; 2894981; -.
DR   KEGG; kla:KLLA0_F04543g; -.
DR   eggNOG; ENOG502S1G1; Eukaryota.
DR   HOGENOM; CLU_095038_0_0_1; -.
DR   InParanoid; Q6CLA4; -.
DR   OMA; GHAMEAK; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031404; Rrt14.
DR   Pfam; PF17075; RRT14; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..201
FT                   /note="Regulator of rDNA transcription 14"
FT                   /id="PRO_0000404342"
FT   REGION          24..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          147..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   201 AA;  23251 MW;  771E4A08177FA77E CRC64;
     MSSLAAAHAT NAVNALLQSV LPGSASVNAE RKKTSRDKGS KAQLIDRNLK KRVEVQEKDV
     YRIKKREKKM LRKKISGRKE VQEDIEQKAK LQVLRKHQVD NSLTDHEKSY LDKVVKKNVR
     NLKSWDYDDK EELLDLQKQI LANSEDSKKV RKVKSRRQKK KQFKEKLPQS IQDHRYKALT
     PGLAPVGASD EEESEDEDED Y