ID   RRT14_KOMPG             Reviewed;         219 AA.
AC   C4R6W8;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Regulator of rDNA transcription 14;
GN   Name=RRT14; OrderedLocusNames=PAS_chr4_0117;
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864;
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   -!- FUNCTION: Involved in ribosome biogenesis, probably through modulation
CC       of rDNA transcription. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRT14 family. {ECO:0000305}.
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DR   EMBL; FN392322; CAY71343.1; -; Genomic_DNA.
DR   RefSeq; XP_002493522.1; XM_002493477.1.
DR   AlphaFoldDB; C4R6W8; -.
DR   SMR; C4R6W8; -.
DR   STRING; 4922.CAY71343; -.
DR   EnsemblFungi; CAY71343; CAY71343; PAS_chr4_0117.
DR   GeneID; 8201203; -.
DR   KEGG; ppa:PAS_chr4_0117; -.
DR   eggNOG; ENOG502SG80; Eukaryota.
DR   HOGENOM; CLU_095038_0_0_1; -.
DR   InParanoid; C4R6W8; -.
DR   Proteomes; UP000000314; Chromosome 4.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031404; Rrt14.
DR   Pfam; PF17075; RRT14; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..219
FT                   /note="Regulator of rDNA transcription 14"
FT                   /id="PRO_0000404346"
FT   REGION          153..219
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        153..174
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..219
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   219 AA;  25163 MW;  FEF981359A382300 CRC64;
     MNKFSSDSSR TTAQSTINKL LVNLIPGSQL NDAKVAKKAK KSSSAKIISD QIGSRMEFKR
     NEEKRRKFLK QNNLKKRKMK RKSKDLEAQL ERIARLSNIK ELQQMSEDSN DPLLDQVIDK
     KITALLSWTT DNSELGTEIE KLKKDILNTD NEEVRRRKSY RDEEREEAEF RSEVEKGSIA
     YPGLTPGLAP VGLSDDEDDE EEDESDGFDK EEEEDQFSE