RRT14_LACTC
ID RRT14_LACTC Reviewed; 197 AA.
AC C5DMI3;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 44.
DE RecName: Full=Regulator of rDNA transcription 14;
GN Name=RRT14; OrderedLocusNames=KLTH0G09174g;
OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS (Yeast) (Kluyveromyces thermotolerans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=559295;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- FUNCTION: Involved in ribosome biogenesis, probably through modulation
CC of rDNA transcription. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRT14 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU928171; CAR24994.1; -; Genomic_DNA.
DR RefSeq; XP_002555431.1; XM_002555385.1.
DR AlphaFoldDB; C5DMI3; -.
DR SMR; C5DMI3; -.
DR STRING; 559295.C5DMI3; -.
DR EnsemblFungi; CAR24994; CAR24994; KLTH0G09174g.
DR GeneID; 8293708; -.
DR KEGG; lth:KLTH0G09174g; -.
DR eggNOG; ENOG502S1G1; Eukaryota.
DR HOGENOM; CLU_095038_0_0_1; -.
DR InParanoid; C5DMI3; -.
DR OMA; GHAMEAK; -.
DR OrthoDB; 1637700at2759; -.
DR Proteomes; UP000002036; Chromosome G.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR InterPro; IPR031404; Rrt14.
DR Pfam; PF17075; RRT14; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..197
FT /note="Regulator of rDNA transcription 14"
FT /id="PRO_0000404343"
FT REGION 25..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 197 AA; 22493 MW; D4850D00A501134D CRC64;
MSSASAKAQA TAAVNNVLSL VLPGSAKIDH NSTKRQNNSK GSKAQLINAN LKKAVRVRER
DAHSIKKREQ RNRRKLQRAR QLAEDKVDQQ AKLDILRKHR EEDSLTAKER KFLNKVINKN
VRDLKSWDVD AEELHELQES VLRNTSQRSS LQKRKRKQRR DDFDESKKPV SGDHRYPGLT
PGLAPVGLSD EEDSDEE