RRT14_LODEL
ID RRT14_LODEL Reviewed; 240 AA.
AC A5DXV0;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 46.
DE RecName: Full=Regulator of rDNA transcription 14;
GN Name=RRT14; ORFNames=LELG_02187;
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC YB-4239;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Involved in ribosome biogenesis, probably through modulation
CC of rDNA transcription. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRT14 family. {ECO:0000305}.
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DR EMBL; CH981525; EDK44008.1; -; Genomic_DNA.
DR RefSeq; XP_001527358.1; XM_001527308.1.
DR AlphaFoldDB; A5DXV0; -.
DR SMR; A5DXV0; -.
DR STRING; 379508.A5DXV0; -.
DR EnsemblFungi; EDK44008; EDK44008; LELG_02187.
DR GeneID; 5233657; -.
DR KEGG; lel:LELG_02187; -.
DR VEuPathDB; FungiDB:LELG_02187; -.
DR eggNOG; ENOG502S1G1; Eukaryota.
DR HOGENOM; CLU_095038_0_0_1; -.
DR InParanoid; A5DXV0; -.
DR OMA; IKYNHIK; -.
DR OrthoDB; 1637700at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR InterPro; IPR031404; Rrt14.
DR Pfam; PF17075; RRT14; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..240
FT /note="Regulator of rDNA transcription 14"
FT /id="PRO_0000404344"
FT REGION 28..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 215..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 240 AA; 27328 MW; 897D5AD90F02FB53 CRC64;
MASFTSNASK HQAELTVNRM FADILHTQPL RSAKSTTSNK SKSASKFGND RKALSMPTPL
SSTQILSQQL QPQLQQTRLS LKTGKSSQNN NKVKKLLKKK HEQDKKFQKF IKYSMIKNKM
STDPESLTLE EHKYLKKLAK RNINALQKYS KIDDFEIEQE MSSVKNELLK DLAPKKQTRL
RKKLAIPAKK GSARSNANNQ INDFDYERKL QKGLISAPGL TPGLAPVDYD DDEEEEEEED