RRT14_PICGU
ID RRT14_PICGU Reviewed; 191 AA.
AC A5DFI4;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 08-FEB-2011, sequence version 3.
DT 25-MAY-2022, entry version 41.
DE RecName: Full=Regulator of rDNA transcription 14;
GN Name=RRT14; ORFNames=PGUG_02035;
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Involved in ribosome biogenesis, probably through modulation
CC of rDNA transcription. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRT14 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EDK37937.2; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH408156; EDK37937.2; ALT_INIT; Genomic_DNA.
DR RefSeq; XP_001486364.1; XM_001486314.1.
DR AlphaFoldDB; A5DFI4; -.
DR SMR; A5DFI4; -.
DR STRING; 4929.XP_001486364.1; -.
DR EnsemblFungi; EDK37937; EDK37937; PGUG_02035.
DR GeneID; 5127701; -.
DR KEGG; pgu:PGUG_02035; -.
DR eggNOG; ENOG502S1G1; Eukaryota.
DR HOGENOM; CLU_095038_0_0_1; -.
DR InParanoid; A5DFI4; -.
DR OrthoDB; 1637700at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR InterPro; IPR031404; Rrt14.
DR Pfam; PF17075; RRT14; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..191
FT /note="Regulator of rDNA transcription 14"
FT /id="PRO_0000404345"
FT REGION 34..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 145..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 191 AA; 21595 MW; F0078D967B89E29D CRC64;
MSFSSQSSKS SAESTLQKFL SGIVPVEAVQ AGKARSQSKA QSVNNQLKTR ALSADEVRRL
QKKAKLKQQR KLKKQQEEAK KVNKLAKHQI IKSHKENNEL TVEEEKYLNK IVKRNANSLS
RLSEIEDYEL KSELESLQEE ILAAQRKSNK KTKQKSKKDF NEKLKRGKIS YPGLTPGLAP
VGLDDDDEDS D