RRT16_YEAST
ID RRT16_YEAST Reviewed; 142 AA.
AC P50943;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=Putative regulator of rDNA transcription protein 16;
GN Name=RRT16; OrderedLocusNames=YNL105W; ORFNames=N2169;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 96604 / S288c / FY1679;
RX PubMed=8701612;
RX DOI=10.1002/(sici)1097-0061(19960330)12:4<403::aid-yea923>3.0.co;2-h;
RA Saiz J.E., Buitrago M.J., Soler A., del Rey F., Revuelta J.L.;
RT "The sequence of a 21.3 kb DNA fragment from the left arm of yeast
RT chromosome XIV reveals LEU4, MET4, POL1, RAS2, and six new open reading
RT frames.";
RL Yeast 12:403-409(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169873;
RA Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K.,
RA Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K.,
RA Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M.,
RA Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F.,
RA Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F.,
RA Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C.,
RA Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A.,
RA Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H.,
RA Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L.,
RA Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R.,
RA Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D.,
RA Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A.,
RA Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C.,
RA Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F.,
RA Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G.,
RA Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M.,
RA Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its
RT evolutionary implications.";
RL Nature 387:93-98(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP GENE NAME.
RX PubMed=19270272; DOI=10.1534/genetics.108.100313;
RA Hontz R.D., Niederer R.O., Johnson J.M., Smith J.S.;
RT "Genetic identification of factors that modulate ribosomal DNA
RT transcription in Saccharomyces cerevisiae.";
RL Genetics 182:105-119(2009).
CC -!- FUNCTION: Identified in a screen for mutants with decreased levels of
CC rDNA transcription.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- MISCELLANEOUS: Almost completely overlaps INP52. {ECO:0000305}.
CC -!- CAUTION: Product of a dubious gene prediction unlikely to encode a
CC functional protein. Because of that it is not part of the S.cerevisiae
CC S288c complete/reference proteome set. {ECO:0000305|PubMed:24374639}.
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DR EMBL; Z50161; CAA90521.1; -; Genomic_DNA.
DR EMBL; Z71382; CAA95983.1; -; Genomic_DNA.
DR EMBL; AY693304; AAT93323.1; -; Genomic_DNA.
DR PIR; S58247; S58247.
DR AlphaFoldDB; P50943; -.
DR DIP; DIP-3937N; -.
DR IntAct; P50943; 2.
DR STRING; 4932.YNL105W; -.
DR PaxDb; P50943; -.
DR EnsemblFungi; YNL105W_mRNA; YNL105W; YNL105W.
DR SGD; S000005049; RRT16.
DR HOGENOM; CLU_1817308_0_0_1; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 5: Uncertain;
KW Membrane; Transcription; Transcription regulation; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..142
FT /note="Putative regulator of rDNA transcription protein 16"
FT /id="PRO_0000203437"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 142 AA; 16168 MW; 8DC57B02E6829AC7 CRC64;
MSMKSHLELF KQKKSTAYIL LTVLFGIGWA TLDLPVMVAM NIRPSISMRP IKPYISWLDS
LLKPLPFNSA FGTNSTAHVD LREFLLFIGL NTSPCVSETI AIFLVCCFDR SIFIATEYLF
LILLPLRGLC HQFCEQKYVE TI
