ID   RRT5_ASHGO              Reviewed;         466 AA.
AC   Q75AP6;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Regulator of rDNA transcription protein 5;
GN   Name=RRT5; OrderedLocusNames=ADL126C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: May be involved in the modulation of rDNA transcription.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRT5 family. {ECO:0000305}.
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DR   EMBL; AE016817; AAS51794.1; -; Genomic_DNA.
DR   RefSeq; NP_983970.1; NM_209323.1.
DR   AlphaFoldDB; Q75AP6; -.
DR   STRING; 33169.AAS51794; -.
DR   EnsemblFungi; AAS51794; AAS51794; AGOS_ADL126C.
DR   GeneID; 4620113; -.
DR   KEGG; ago:AGOS_ADL126C; -.
DR   eggNOG; ENOG502RZDM; Eukaryota.
DR   HOGENOM; CLU_586559_0_0_1; -.
DR   InParanoid; Q75AP6; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   CDD; cd12409; RRM1_RRT5; 1.
DR   CDD; cd12410; RRM2_RRT5; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR034244; Rrt5_RRM1.
DR   InterPro; IPR034247; Rrt5_RRM2.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50102; RRM; 2.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; RNA-binding; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..466
FT                   /note="Regulator of rDNA transcription protein 5"
FT                   /id="PRO_0000404354"
FT   DOMAIN          49..132
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          188..270
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          311..347
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          406..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        311..342
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   466 AA;  52326 MW;  AD69B926F082B94F CRC64;
     MSDQPAQSDL PDQGALPPQE AAQPQAVRED PQPQQCAQQV LFEQQGAQHR VYISNLSQDA
     TEEALTEFLK DFHPVSVLIP SQSVRGFQKT SVRPLGIAYV EFKDADTAAK VILELNGVTF
     MDRELRLRYH IPFKSEKEKL ARGPNKFRQI QRRLSELRRR NSDAGATVTT DNGPQVDAAA
     VPREMSKVTI YVGRLPGRTT DKDLRTYFHE YLPQEIIVFK HRQFRGWRIR RHVTAAVITF
     PDHERQESAL ESLSNLPFNG RTVRMAPAFE DKLAEIRAEV QRMAVEQQLP QPASNLGIYI
     GNNLIAMQPL QTRKADQQSL QSQHSPQNAA EDQTITAPPP SQQQLPQLQP IAPPLSLQPL
     NPVENTQPVQ GLDLSIPREH EEVVRGQPLL RLQKLQMIQR LQRLHRQKQR QQIQQEPAAQ
     PAAQPAAQPA TEAAVAPQLV PEQEAHQAAA QAEPQQVLER PIAAGA