ID   RRT5_DEBHA              Reviewed;         355 AA.
AC   Q6BW07;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   04-NOV-2008, sequence version 2.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Regulator of rDNA transcription protein 5;
GN   Name=RRT5; OrderedLocusNames=DEHA2B15246g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in the modulation of rDNA transcription.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRT5 family. {ECO:0000305}.
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DR   EMBL; CR382134; CAG85623.2; -; Genomic_DNA.
DR   RefSeq; XP_457612.2; XM_457612.1.
DR   AlphaFoldDB; Q6BW07; -.
DR   STRING; 4959.XP_457612.2; -.
DR   EnsemblFungi; CAG85623; CAG85623; DEHA2B15246g.
DR   GeneID; 2913584; -.
DR   KEGG; dha:DEHA2B15246g; -.
DR   VEuPathDB; FungiDB:DEHA2B15246g; -.
DR   eggNOG; ENOG502RZDM; Eukaryota.
DR   HOGENOM; CLU_042558_0_0_1; -.
DR   InParanoid; Q6BW07; -.
DR   OMA; IWIFRTR; -.
DR   OrthoDB; 1442049at2759; -.
DR   Proteomes; UP000000599; Chromosome B.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   CDD; cd12410; RRM2_RRT5; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR034247; Rrt5_RRM2.
DR   Pfam; PF00076; RRM_1; 1.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50102; RRM; 2.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; RNA-binding; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..355
FT                   /note="Regulator of rDNA transcription protein 5"
FT                   /id="PRO_0000404357"
FT   DOMAIN          21..88
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          170..256
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          272..299
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          314..355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        314..329
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        330..344
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   355 AA;  39814 MW;  0D59669F672A989F CRC64;
     MSLVIPESPM FEVANNGKKS SRVYIKNLHF NTSEEELEVF LKKYEPRHRP FGIAYAEFSS
     VEQASKVVKD LNGALFKDRQ IFVKLHVPFS PTGKPIFGRR KTSSGAEKLG DASNKVNLSA
     KTDKPLSSDT KDFDGVASTV PRSINIEDIP FTDEPKKVQD EDVQKKLSND TIFIGNAVDK
     TVDKDVREFF KDYYPTQVFI FRGANQKRMQ RTISLRQKTV SVLVTLKKEE DLSKAISELN
     SKKLNGRAVY LKAAHLSKIE EVVNAAKITA VPSKSPPTTA TADDEAQEQK GNTTAETSTL
     LEMFKDTQKK IQGKYKETIE KQIRPSDTPL GEEEEEEEEG DETKQGVPNE EMIVA